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    dsdX D-serine transporter [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 949103, updated on 3-Dec-2024

    Summary

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    Official Symbol
    dsdX
    Official Full Name
    D-serine transporter
    Primary source
    ECOCYC:EG10250
    Locus tag
    b2365
    See related
    ASAP:ABE-0007801
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    dsdC; ECK2361; yfdA; yfdD
    Summary
    DsdX has been functionally characterized in Escherichia coli strain CFT073 (Anfora, 2006). [More information is available at EcoGene: EG10250]. DsdX is a transporter of unknown function belonging to the Gnt family of gluconate transporters . [More information is available at EcoCyc: EG10250].
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    Genomic context

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    Sequence:
    NC_000913.3 (2477847..2479184)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene DNA-binding transcriptional dual regulator DsdC Neighboring gene D-serine ammonia-lyase Neighboring gene tripartite efflux pump membrane subunit EmrY Neighboring gene tripartite efflux pump membrane fusion protein EmrK

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. DsdX is the second D-serine transporter in uropathogenic Escherichia coli clinical isolate CFT073. Anfora AT, et al. J Bacteriol, 2006 Sep. PMID 16952954, Free PMC Article
    2. Analysis of the gluconate (gnt) operon of Bacillus subtilis. Reizer A, et al. Mol Microbiol, 1991 May. PMID 1659648
    3. Transfer of a gene for sucrose utilization into Escherichia coli K12, and consequent failure of expression of genes for D-serine utilization. Alaeddinoglu NG, et al. J Gen Microbiol, 1979 Jan. PMID 372492
    4. Physical mapping of the Escherichia coli D-serine deaminase region: contiguity of the dsd structural and regulatory genes. Carothers AM, et al. J Bacteriol, 1980 Apr. PMID 6246062, Free PMC Article
    5. Identification and control of synthesis of the dsdC activator protein. McFall E, et al. J Bacteriol, 1983 Feb. PMID 6296057, Free PMC Article

    See all (22) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables D-serine transmembrane transporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables gluconate transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables gluconate transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within D-serine transmembrane transport ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    acts_upstream_of_or_within DNA damage response IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in amino acid transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in gluconate transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in gluconate transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    D-serine transporter

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      2477847..2479184
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_416866.1 D-serine transporter [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_416866.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A7D7IMB7
      Conserved Domains (1) summary
      PRK09921
      Location:1 → 445
      PRK09921; permease DsdX; Provisional
    Nucleotide Protein
    Heading Accession and Version

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