U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    dsdA D-serine ammonia-lyase [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 946837, updated on 3-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    dsdA
    Official Full Name
    D-serine ammonia-lyase
    Primary source
    ECOCYC:EG10249
    Locus tag
    b2366
    See related
    ASAP:ABE-0007804
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK2362
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    Sequence:
    NC_000913.3 (2479202..2480530)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene DNA-binding transcriptional dual regulator DsdC Neighboring gene D-serine transporter Neighboring gene tripartite efflux pump membrane subunit EmrY Neighboring gene tripartite efflux pump membrane fusion protein EmrK

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Metagenome resource for D-serine utilization in a DsdA-disrupted Escherichia coli. Lim MY, et al. J Microbiol Biotechnol, 2011 Apr. PMID 21532320
    2. D-Serine dehydratase from Escherichia coli. Essential arginine residue at the pyridoxal 5'-phosphate binding site. Kazarinoff MN, et al. J Biol Chem, 1976 Oct 25. PMID 789365
    3. Sequence studies on D-serine dehydratase of Escherichia coli. Primary structure of the tryptic phosphopyridoxyl peptide and of the N-terminus. Schiltz E, et al. Eur J Biochem, 1976 Dec. PMID 795658
    4. Effect of potassium ion on the phosphorus-31 nuclear magnetic resonance spectrum of the pyridoxal 5'-phosphate cofactor of Escherichia coli D-serine dehydratase. Kojiro CL, et al. Arch Biochem Biophys, 1989 Jan. PMID 2643389
    5. The dsdA gene from Escherichia coli provides a novel selectable marker for plant transformation. Erikson O, et al. Plant Mol Biol, 2005 Feb. PMID 15830131

    See all (26) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Two alternative genetic resources for D-serine dehydratase were identified in DsdA-disrupted strain.
      Title: Metagenome resource for D-serine utilization in a DsdA-disrupted Escherichia coli.
    2. N-terminus verified by Edman degradation on complete protein
      Title: Sequence of Escherichia coli D-serine dehydratase. Location of the pyridoxal-phosphate binding site.
    Submit: New GeneRIF Correction

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables D-serine ammonia-lyase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables D-serine ammonia-lyase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables D-serine ammonia-lyase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ammonia-lyase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables hydro-lyase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables hydro-lyase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables lyase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables pyridoxal phosphate binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables pyridoxal phosphate binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables pyridoxal phosphate binding IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in D-amino acid metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in D-serine catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within D-serine catabolic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within D-serine catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within D-serine metabolic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within DNA damage response IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within detoxification of nitrogen compound IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    D-serine ammonia-lyase
    NP_416867.1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      2479202..2480530
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_416867.1 D-serine ammonia-lyase [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_416867.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A8S7EK81
      Conserved Domains (1) summary
      PRK02991
      Location:6 → 442
      PRK02991; D-serine dehydratase; Provisional
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.