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    yfiC tRNA m(6)A37 methyltransferase [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 947047, updated on 17-Dec-2024

    Summary

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    Official Symbol
    yfiC
    Official Full Name
    tRNA m(6)A37 methyltransferase
    Primary source
    ECOCYC:EG11538
    Locus tag
    b2575
    See related
    ASAP:ABE-0008473
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK2573; trmM
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    Genomic context

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    Sequence:
    NC_000913.3 (2712027..2712764, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene anti-sigma factor stabilizing protein RseB Neighboring gene anti-sigma-E factor RseA Neighboring gene RNA polymerase sigma factor RpoE Neighboring gene rpoE leader peptide Neighboring gene L-aspartate oxidase Neighboring gene ATP-dependent RNA helicase SrmB Neighboring gene putative LysR-type DNA-binding transcriptional regulator YfiE

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. MODOMICS: a database of RNA modification pathways. 2008 update. Czerwoniec A, et al. Nucleic Acids Res, 2009 Jan. PMID 18854352, Free PMC Article
    2. The yfiC gene of E. coli encodes an adenine-N6 methyltransferase that specifically modifies A37 of tRNA1Val(cmo5UAC). Golovina AY, et al. RNA, 2009 Jun. PMID 19383770, Free PMC Article
    3. Comparative genomics and evolution of proteins involved in RNA metabolism. Anantharaman V, et al. Nucleic Acids Res, 2002 Apr 1. PMID 11917006, Free PMC Article
    4. Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110. Hayashi K, et al. Mol Syst Biol, 2006. PMID 16738553, Free PMC Article
    5. The complete genome sequence of Escherichia coli K-12. Blattner FR, et al. Science, 1997 Sep 5. PMID 9278503

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables N-methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables S-adenosylmethionine-dependent methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables tRNA (adenine-N6)-methyltransferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables tRNA (adenine-N6)-methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in methylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within tRNA methylation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in tRNA processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    tRNA m(6)A37 methyltransferase
    NP_417070.2

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      2712027..2712764 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_417070.2 tRNA m(6)A37 methyltransferase [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_417070.2

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A5B9AR34, A0A8T5ZI23
      Conserved Domains (1) summary
      COG4123
      Location:1 → 245
      TrmN6; tRNA1(Val) A37 N6-methylase TrmN6 [Translation, ribosomal structure and biogenesis]
    Nucleotide Protein
    Heading Accession and Version

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