U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    gudX glucarate dehydratase-related protein [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 947261, updated on 3-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    gudX
    Official Full Name
    glucarate dehydratase-related protein
    Primary source
    ECOCYC:G7446
    Locus tag
    b2788
    See related
    ASAP:ABE-0009136
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK2782; ygcY
    Summary
    GudX (GlucD-related protein, GlucDRP) has similarity to the functional D-glucarate dehydratase, GudD, which is encoded in a probable operon downstream of gudX. [More information is available at EcoCyc: G7446].
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    Sequence:
    NC_000913.3 (2919406..2920746, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene sensor histidine kinase BarA Neighboring gene D-glucarate dehydratase Neighboring gene galactarate/D-glucarate transporter GudP Neighboring gene putative flavodoxin YqcA

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. A common regulator for the operons encoding the enzymes involved in D-galactarate, D-glucarate, and D-glycerate utilization in Escherichia coli. Monterrubio R, et al. J Bacteriol, 2000 May. PMID 10762278, Free PMC Article
    2. Evolution of enzymatic activities in the enolase superfamily: characterization of the (D)-glucarate/galactarate catabolic pathway in Escherichia coli. Hubbard BK, et al. Biochemistry, 1998 Oct 13. PMID 9772162
    3. Divergent evolution in the enolase superfamily: the interplay of mechanism and specificity. Gerlt JA, et al. Arch Biochem Biophys, 2005 Jan 1. PMID 15581566
    4. Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110. Hayashi K, et al. Mol Syst Biol, 2006. PMID 16738553, Free PMC Article
    5. The complete genome sequence of Escherichia coli K-12. Blattner FR, et al. Science, 1997 Sep 5. PMID 9278503

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables glucarate dehydratase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables lyase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in D-glucarate catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in amino acid catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within cellular catabolic process ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    glucarate dehydratase-related protein

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      2919406..2920746 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_417268.1 glucarate dehydratase-related protein [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_417268.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A376FXD6
      Conserved Domains (1) summary
      cd03323
      Location:8 → 416
      D-glucarate_dehydratase; D-Glucarate dehydratase (GlucD) catalyzes the dehydration of both D-glucarate and L-idarate to form 5-keto-4-deoxy-D-glucarate (5-KDG) , the initial reaction of the catabolic pathway for (D)-glucarate. GlucD belongs to the enolase superfamily of enzymes, ...
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.