U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    gcvT aminomethyltransferase [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 947390, updated on 3-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    gcvT
    Official Full Name
    aminomethyltransferase
    Primary source
    ECOCYC:EG11442
    Locus tag
    b2905
    See related
    ASAP:ABE-0009536
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK2900
    Summary
    Together with GcvH, GcvP and E3 (Lpd), GvcT forms a loosely associated complex known as the glycine cleavage system. [More information is available at EcoCyc: EG11442].
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    Sequence:
    NC_000913.3 (3049573..3050667, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene glycine decarboxylase Neighboring gene glycine cleavage system H protein Neighboring gene protein YqfI Neighboring gene 2-octaprenylphenol 6-hydroxylase

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Identification of the folate binding sites on the Escherichia coli T-protein of the glycine cleavage system. Okamura-Ikeda K, et al. J Biol Chem, 1999 Jun 18. PMID 10364177
    2. [Mapping of regulatory domain of T-protein from Escherichia coli]. Zhang H, et al. Zhejiang Da Xue Xue Bao Yi Xue Ban, 2005 Mar. PMID 15812896
    3. Regulation of one-carbon biosynthesis and utilization in Escherichia coli. Meedel TH, et al. J Bacteriol, 1974 Jun. PMID 4598009, Free PMC Article
    4. Characterization of the gcv control region from Escherichia coli. Stauffer LT, et al. J Bacteriol, 1994 Oct. PMID 7928983, Free PMC Article
    5. The amino-terminal region of the Escherichia coli T-protein of the glycine cleavage system is essential for proper association with H-protein. Okamura-Ikeda K, et al. Eur J Biochem, 1999 Sep. PMID 10491090

    See all (32) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. N-terminus verified by Edman degradation on mature peptide
      Title: Comparing the predicted and observed properties of proteins encoded in the genome of Escherichia coli K-12.
    Submit: New GeneRIF Correction

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables aminomethyltransferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables aminomethyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transaminase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in glycine catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in glycine decarboxylation via glycine cleavage system IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in glycine decarboxylation via glycine cleavage system NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    involved_in one-carbon metabolic process NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of glycine cleavage complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of glycine cleavage complex NAS
    Non-traceable Author Statement
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    aminomethyltransferase
    NP_417381.1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      3049573..3050667 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_417381.1 aminomethyltransferase [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_417381.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A5B9ASK1, A0A8S7EFZ2
      Conserved Domains (1) summary
      PRK00389
      Location:1 → 362
      gcvT; glycine cleavage system aminomethyltransferase GcvT
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.