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    hybG hydrogenase maturation factor HybG [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 948020, updated on 3-Dec-2024

    Summary

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    Official Symbol
    hybG
    Official Full Name
    hydrogenase maturation factor HybG
    Primary source
    ECOCYC:EG11805
    Locus tag
    b2990
    See related
    ASAP:ABE-0009816
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK2984
    Summary
    [More information is available at EcoGene: EG11805]. HybG is a chaperone-like protein which is required for the generation of active hydrogenase 2. [More information is available at EcoCyc: EG11805].
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    Genomic context

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    Sequence:
    NC_000913.3 (3139716..3139964, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene fused glutathionylspermidine amidase/glutathionylspermidine synthetase Neighboring gene disulfide reductase/organic hydroperoxide reductase Neighboring gene hydrogenase maturation protein HybF Neighboring gene hydrogenase 2-specific chaperone Neighboring gene hydrogenase 2 maturation protease Neighboring gene hydrogenase 2 large subunit

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Native mass spectrometry identifies the HybG chaperone as carrier of the Fe(CN)(2)CO group during maturation of E. coli [NiFe]-hydrogenase 2. Arlt C, et al. Sci Rep, 2021 Dec 21. PMID 34934150, Free PMC Article
    2. [NiFe]-hydrogenase maturation in vitro: analysis of the roles of the HybG and HypD accessory proteins1. Soboh B, et al. Biochem J, 2014 Dec 1. PMID 25184670
    3. Maturation of [NiFe]-hydrogenases in Escherichia coli. Forzi L, et al. Biometals, 2007 Jun. PMID 17216401
    4. Interactions of the Escherichia coli hydrogenase biosynthetic proteins: HybG complex formation. Butland G, et al. FEBS Lett, 2006 Jan 23. PMID 16412426
    5. The [NiFe]-hydrogenase accessory chaperones HypC and HybG of Escherichia coli are iron- and carbon dioxide-binding proteins. Soboh B, et al. FEBS Lett, 2013 Aug 19. PMID 23851071

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables carbon dioxide binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables carbon dioxide binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables identical protein binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables iron ion binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables iron ion binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein maturation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein maturation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in protein maturation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in protein-containing complex assembly IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    hydrogenase maturation factor HybG

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      3139716..3139964 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_417464.1 hydrogenase maturation factor HybG [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_417464.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A5N8HFE5
      Conserved Domains (1) summary
      PRK10413
      Location:1 → 82
      PRK10413; hydrogenase maturation factor HybG
    Nucleotide Protein
    Heading Accession and Version

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