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    yrbG putative transport protein YrbG [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 947730, updated on 3-Dec-2024

    Summary

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    Official Symbol
    yrbG
    Official Full Name
    putative transport protein YrbG
    Primary source
    ECOCYC:EG12802
    Locus tag
    b3196
    See related
    ASAP:ABE-0010502
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK3185
    Summary
    YrbG has duplicate domains with opposite topologies. [More information is available at EcoGene: EG12802]. YrbG is an uncharacterized member of the CaCA family of metal cation exchangers . [More information is available at EcoCyc: EG12802].
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    Genomic context

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    Sequence:
    NC_000913.3 (3340275..3341252)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene intermembrane phospholipid transport system, integral membrane subunit MlaE Neighboring gene intermembrane phospholipid transport system, ATP binding subunit MlaF Neighboring gene D-arabinose 5-phosphate isomerase KdsD Neighboring gene 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase KdsC Neighboring gene lipopolysaccharide transport system protein LptC

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. pH and monovalent cations regulate cytosolic free Ca(2+) in E. coli. Naseem R, et al. Biochim Biophys Acta, 2008 Jun. PMID 18342619
    2. Phylogenetic characterization of novel transport protein families revealed by genome analyses. Saier MH Jr, et al. Biochim Biophys Acta, 1999 Feb 25. PMID 10082980
    3. The internal repeats in the Na+/Ca2+ exchanger-related Escherichia coli protein YrbG have opposite membrane topologies. Sääf A, et al. J Biol Chem, 2001 Jun 1. PMID 11259419
    4. TCDB: the Transporter Classification Database for membrane transport protein analyses and information. Saier MH Jr, et al. Nucleic Acids Res, 2006 Jan 1. PMID 16381841, Free PMC Article
    5. Experimentally constrained topology models for 51,208 bacterial inner membrane proteins. Granseth E, et al. J Mol Biol, 2005 Sep 23. PMID 16120447

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables calcium channel activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables calcium, potassium:sodium antiporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables transmembrane transporter activity RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in calcium ion transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in intracellular calcium ion homeostasis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in potassium ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in sodium ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within transmembrane transport RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    putative transport protein YrbG

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      3340275..3341252
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_417663.1 putative transport protein YrbG [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_417663.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A376FXW6
      Conserved Domains (1) summary
      PRK10734
      Location:1 → 325
      PRK10734; putative calcium/sodium:proton antiporter; Provisional
    Nucleotide Protein
    Heading Accession and Version

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