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    nudE ADP-sugar diphosphatase NudE [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 947906, updated on 3-Dec-2024

    Summary

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    Official Symbol
    nudE
    Official Full Name
    ADP-sugar diphosphatase NudE
    Primary source
    ECOCYC:G7740
    Locus tag
    b3397
    See related
    ASAP:ABE-0011086
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK3384; yrfE
    Summary
    Nudix hydrolase. [More information is available at EcoGene: EG12926]. NudE belongs to the family of Nudix hydrolases . [More information is available at EcoCyc: G7740].
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    Genomic context

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    Sequence:
    NC_000913.3 (3525589..3526149, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene DNA utilization protein HofN Neighboring gene DNA utilization protein HofM Neighboring gene peptidoglycan glycosyltransferase/peptidoglycan DD-transpeptidase MrcA Neighboring gene inner membrane protein IgaA Neighboring gene purine nucleotidase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Orf186 represents a new member of the Nudix hydrolases, active on adenosine(5')triphospho(5')adenosine, ADP-ribose, and NADH. O'Handley SF, et al. J Biol Chem, 1998 Feb 6. PMID 9452430
    2. Reconstruction of Escherichia coli mrcA (PBP 1a) mutants lacking multiple combinations of penicillin binding proteins. Meberg BM, et al. J Bacteriol, 2001 Oct. PMID 11567017, Free PMC Article
    3. Structural analysis of a set of proteins resulting from a bacterial genomics project. Badger J, et al. Proteins, 2005 Sep 1. PMID 16021622
    4. The MutT proteins or "Nudix" hydrolases, a family of versatile, widely distributed, "housecleaning" enzymes. Bessman MJ, et al. J Biol Chem, 1996 Oct 11. PMID 8810257
    5. Localization, annotation, and comparison of the Escherichia coli K-12 proteome under two states of growth. Lopez-Campistrous A, et al. Mol Cell Proteomics, 2005 Aug. PMID 15911532

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables ADP-ribose diphosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ADP-sugar diphosphatase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables ADP-sugar diphosphatase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables magnesium ion binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein homodimerization activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in nucleoside phosphate metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in ribose phosphate metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ADP-sugar diphosphatase NudE
    NP_417856.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      3525589..3526149 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_417856.1 ADP-sugar diphosphatase NudE [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_417856.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A2X3J8P9
      Conserved Domains (1) summary
      PRK11762
      Location:1 → 184
      nudE; adenosine nucleotide hydrolase NudE; Provisional
    Nucleotide Protein
    Heading Accession and Version

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