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    livG branched chain amino acid/phenylalanine ABC transporter ATP binding subunit LivG [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 947967, updated on 3-Dec-2024

    Summary

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    Official Symbol
    livG
    Official Full Name
    branched chain amino acid/phenylalanine ABC transporter ATP binding subunit LivG
    Primary source
    ECOCYC:EG10537
    Locus tag
    b3455
    See related
    ASAP:ABE-0011284
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK3439; hrbB; hrbC; hrbD
    Summary
    LivFGHMJ and LivFGHMK are two ATP-dependent high-affinity branched-chain amino acid transport system and are members of the ATP Binding Cassette (ABC) Superfamily of transporters . [More information is available at EcoCyc: EG10537].
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    Genomic context

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    Sequence:
    NC_000913.3 (3593439..3594206, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene sn-glycerol 3-phosphate ABC transporter periplasmic binding protein Neighboring gene branched chain amino acid/phenylalanine ABC transporter ATP binding subunit LivF Neighboring gene branched chain amino acid/phenylalanine ABC transporter membrane subunit LivM Neighboring gene branched chain amino acid/phenylalanine ABC transporter membrane subunit LivH Neighboring gene L-leucine/L-phenylalanine ABC transporter periplasmic binding protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Transport of L-4-azaleucine in Escherichia coli. Harrison LI, et al. J Bacteriol, 1975 Jun. PMID 238951, Free PMC Article
    2. Genetic and biochemical studies of transport systems for branched-chain amino acids in Escherichia coli K-12: isolation and properties of mutants defective in leucine-repressible transport activities. Yamato I, et al. J Bacteriol, 1980 Oct. PMID 6998958, Free PMC Article
    3. Structural and functional analysis of cloned DNA containing genes responsible for branched-chain amino acid transport in Escherichia coli. Oxender DL, et al. Proc Natl Acad Sci U S A, 1980 Mar. PMID 6445555, Free PMC Article
    4. The complete nucleotide sequences of the Escherichia coli LIV-BP and LS-BP genes. Implications for the mechanism of high-affinity branched-chain amino acid transport. Landick R, et al. J Biol Chem, 1985 Jul 15. PMID 3891753
    5. Identification of livG, a membrane-associated component of the branched-chain amino acid transport in Escherichia coli. Nazos PM, et al. J Bacteriol, 1985 Sep. PMID 2993238, Free PMC Article

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP binding ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables L-isoleucine transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables L-isoleucine transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables L-leucine transmembrane transporter activity EXP
    Inferred from Experiment
    more info
    		 PubMed 
    enables L-phenylalanine transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables L-phenylalanine transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables L-valine transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables L-valine transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables branched-chain amino acid transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in D-alanine transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in L-alanine transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in L-isoleucine import across plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in L-valine import across plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within L-valine transmembrane transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in amino acid transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within branched-chain amino acid transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in branched-chain amino acid transport NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within isoleucine transmembrane transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within phenylalanine transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in phenylalanine transport NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    part_of ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 
    located_in membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in membrane NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    branched chain amino acid/phenylalanine ABC transporter ATP binding subunit LivG
    NP_417912.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      3593439..3594206 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_417912.1 branched chain amino acid/phenylalanine ABC transporter ATP binding subunit LivG [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_417912.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A7D7F9S9
      Conserved Domains (1) summary
      PRK11300
      Location:1 → 255
      livG; leucine/isoleucine/valine transporter ATP-binding subunit; Provisional
    Nucleotide Protein
    Heading Accession and Version

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