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    yieF quinone reductase [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 948225, updated on 17-Dec-2024

    Summary

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    Official Symbol
    yieF
    Official Full Name
    quinone reductase
    Primary source
    ECOCYC:EG11723
    Locus tag
    b3713
    See related
    ASAP:ABE-0012146
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    chrR; ECK3706
    Summary
    YieF mutant enzyme Y6 kills HeLa spinner cells. [More information is available at EcoGene: EG11723]. YieF is a flavoprotein containing the FMN cofactor . [More information is available at EcoCyc: EG11723].
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    Genomic context

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    Sequence:
    NC_000913.3 (3894652..3895218)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene efflux pump MdtL Neighboring gene DNA-binding transcriptional dual regulator YidZ Neighboring gene putative phosphopantetheinyl transferase Neighboring gene adenine:H(+) symporter Neighboring gene 6-phosphogluconate phosphatase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Insights into the mode of flavin mononucleotide binding and catalytic mechanism of bacterial chromate reductases: A molecular dynamics simulation study. Pradhan SK, et al. J Cell Biochem, 2019 Oct. PMID 31131470
    2. New enzyme for reductive cancer chemotherapy, YieF, and its improvement by directed evolution. Barak Y, et al. Mol Cancer Ther, 2006 Jan. PMID 16432167
    3. Mechanism of chromate reduction by the Escherichia coli protein, NfsA, and the role of different chromate reductases in minimizing oxidative stress during chromate reduction. Ackerley DF, et al. Environ Microbiol, 2004 Aug. PMID 15250887
    4. Salmonella genomic island 1 multidrug resistance gene clusters in Salmonella enterica serovar Agona isolated in Belgium in 1992 to 2002. Doublet B, et al. Antimicrob Agents Chemother, 2004 Jul. PMID 15215102, Free PMC Article
    5. Effect of chromate stress on Escherichia coli K-12. Ackerley DF, et al. J Bacteriol, 2006 May. PMID 16621832, Free PMC Article

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Insights into the mode of flavin mononucleotide binding and catalytic mechanism of bacterial chromate reductases: A molecular dynamics simulation study.
      Title: Insights into the mode of flavin mononucleotide binding and catalytic mechanism of bacterial chromate reductases: A molecular dynamics simulation study.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    General protein information

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    Preferred Names
    quinone reductase

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      3894652..3895218
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_418169.1 quinone reductase [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_418169.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A2X1NBX7
      Conserved Domains (1) summary
      COG0431
      Location:5 → 181
      SsuE; NAD(P)H-dependent FMN reductase [Energy production and conversion]
    Nucleotide Protein
    Heading Accession and Version

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