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    rffH glucose-1-phosphate thymidylyltransferase 2 [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 948299, updated on 3-Dec-2024

    Summary

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    Official Symbol
    rffH
    Official Full Name
    glucose-1-phosphate thymidylyltransferase 2
    Primary source
    ECOCYC:EG11454
    Locus tag
    b3789
    See related
    ASAP:ABE-0012379
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK3781; yifG
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    Genomic context

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    Sequence:
    NC_000913.3 (3973608..3974489)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene UDP-N-acetylglucosamine 2-epimerase Neighboring gene UDP-N-acetyl-D-mannosamine dehydrogenase Neighboring gene dTDP-glucose 4,6-dehydratase 2 Neighboring gene RffC Neighboring gene dTDP-4-dehydro-6-deoxy-D-glucose transaminase Neighboring gene lipid IIIECA flippase Neighboring gene TDP-N-acetylfucosamine:lipid II N-acetylfucosaminyltransferase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Crystal structure of Escherichia coli glucose-1-phosphate thymidylyltransferase (RffH) complexed with dTTP and Mg2+. Sivaraman J, et al. J Biol Chem, 2002 Nov 15. PMID 12171937
    2. Genetic analysis of the dTDP-rhamnose biosynthesis region of the Escherichia coli VW187 (O7:K1) rfb gene cluster: identification of functional homologs of rfbB and rfbA in the rff cluster and correct location of the rffE gene. Marolda CL, et al. J Bacteriol, 1995 Oct. PMID 7559340, Free PMC Article
    3. Structure of the O antigen of Escherichia coli K-12 and the sequence of its rfb gene cluster. Stevenson G, et al. J Bacteriol, 1994 Jul. PMID 7517391, Free PMC Article
    4. Analysis of the Escherichia coli genome: DNA sequence of the region from 84.5 to 86.5 minutes. Daniels DL, et al. Science, 1992 Aug 7. PMID 1379743
    5. Genome-wide screening of genes required for swarming motility in Escherichia coli K-12. Inoue T, et al. J Bacteriol, 2007 Feb. PMID 17122336, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables glucose-1-phosphate thymidylyltransferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables glucose-1-phosphate thymidylyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables identical protein binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables magnesium ion binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nucleotidyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within O antigen biosynthetic process EXP
    Inferred from Experiment
    more info
    		 PubMed 
    involved_in enterobacterial common antigen biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in polysaccharide biosynthetic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in polysaccharide biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    glucose-1-phosphate thymidylyltransferase 2
    NP_418236.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      3973608..3974489
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_418236.1 glucose-1-phosphate thymidylyltransferase 2 [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_418236.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0AAN3Q1Y7
      Conserved Domains (1) summary
      TIGR01207
      Location:2 → 287
      rmlA; glucose-1-phosphate thymidylyltransferase, short form
    Nucleotide Protein
    Heading Accession and Version

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