U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    bipA 50S ribosomal subunit assembly factor BipA [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 948369, updated on 3-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    bipA
    Official Full Name
    50S ribosomal subunit assembly factor BipA
    Primary source
    ECOCYC:EG11837
    Locus tag
    b3871
    See related
    ASAP:ABE-0012648
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK3864; typA; yihK
    Summary
    BipA is a member of the ribosome-binding GTPase superfamily. [More information is available at EcoCyc: EG11837].
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    Sequence:
    NC_000913.3 (4058407..4060230)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene protein histidine kinase NtrB Neighboring gene glutamine synthetase Neighboring gene putative DNA-binding transcriptional regulator YihL Neighboring gene putative TIM barrel domain-containing protein YihM

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. The GTPase BipA expressed at low temperature in Escherichia coli assists ribosome assembly and has chaperone-like activity. Choi E, et al. J Biol Chem, 2018 Nov 23. PMID 30305394, Free PMC Article
    2. Salmonella typhimurium responses to a bactericidal protein from human neutrophils. Qi SY, et al. Mol Microbiol, 1995 Aug. PMID 8559071
    3. Tyrosine phosphorylation in Escherichia coli. Freestone P, et al. J Mol Biol, 1998 Jun 26. PMID 9642082
    4. BipA affects Ca++ fluxes and phosphorylation of the translocated intimin receptor (Tir/Hp90) in host epithelial cells infected with enteropathogenic E. coli. Farris M, et al. Biochem Soc Trans, 1998 Aug. PMID 9765944
    5. Regulation of the Escherichia coli K5 capsule gene cluster: evidence for the roles of H-NS, BipA, and integration host factor in regulation of group 2 capsule gene clusters in pathogenic E. coli. Rowe S, et al. J Bacteriol, 2000 May. PMID 10781541, Free PMC Article

    See all (34) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. BipA expression was significantly stimulated at 20 degrees C, suggesting that it encodes a cold shock-inducible GTPase.
      Title: The GTPase BipA expressed at low temperature in Escherichia coli assists ribosome assembly and has chaperone-like activity.
    2. N-terminus verified by Edman degradation on complete protein
      Title: Comparing the predicted and observed properties of proteins encoded in the genome of Escherichia coli K-12.
    Submit: New GeneRIF Correction

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables GTPase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables GTPase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables guanosine tetraphosphate binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables guanosine tetraphosphate binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables membrane scission GTPase motor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein folding chaperone IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables rRNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ribosome binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables tRNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein folding IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within response to cold IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within response to cold IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within response to heat IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in ribosomal large subunit assembly IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within ribosomal large subunit assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in ribosome biogenesis IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within translation IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of ribonucleoprotein complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    50S ribosomal subunit assembly factor BipA

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      4058407..4060230
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. YP_026274.1 50S ribosomal subunit assembly factor BipA [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for YP_026274.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A775YXG6, A0A826J2W3, A0A830SKM2
      Conserved Domains (1) summary
      COG1217
      Location:1 → 604
      TypA; Predicted membrane GTPase involved in stress response [Signal transduction mechanisms]
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.