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    frwC putative PTS enzyme IIC component FrwC [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 948448, updated on 17-Dec-2024

    Summary

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    Official Symbol
    frwC
    Official Full Name
    putative PTS enzyme IIC component FrwC
    Primary source
    ECOCYC:EG11908
    Locus tag
    b3949
    See related
    ASAP:ABE-0012928
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK3940; yijJ
    Summary
    FrwCBD PtsA, a putative PTS permease, belongs to the functional superfamily of the phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system (PTS). [More information is available at EcoCyc: EG11908].
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    Genomic context

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    Sequence:
    NC_000913.3 (4142530..4143609)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene fructose-6-phosphate aldolase 2 Neighboring gene putative PTS multiphosphoryl transfer protein PtsA Neighboring gene putative PTS enzyme IIB component FrwB Neighboring gene putative formate acetyltransferase 2 Neighboring gene putative pyruvate formate-lyase 2 activating enzyme PflC

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Novel phosphotransferase system genes revealed by bacterial genome analysis--a gene cluster encoding a unique Enzyme I and the proteins of a fructose-like permease system. Reizer J, et al. Microbiology (Reading), 1995 Apr. PMID 7773398
    2. DNA microarray-based identification of genes controlled by autoinducer 2-stimulated quorum sensing in Escherichia coli. DeLisa MP, et al. J Bacteriol, 2001 Sep. PMID 11514505, Free PMC Article
    3. Analysis of the Escherichia coli genome. IV. DNA sequence of the region from 89.2 to 92.8 minutes. Blattner FR, et al. Nucleic Acids Res, 1993 Nov 25. PMID 8265357, Free PMC Article
    4. Experimentally constrained topology models for 51,208 bacterial inner membrane proteins. Granseth E, et al. J Mol Biol, 2005 Sep 23. PMID 16120447
    5. Global topology analysis of the Escherichia coli inner membrane proteome. Daley DO, et al. Science, 2005 May 27. PMID 15919996

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables carbohydrate:proton symporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein-N(PI)-phosphohistidine-sugar phosphotransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein-phosphocysteine-sugar phosphotransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in fructose import across plasma membrane NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    involved_in phosphoenolpyruvate-dependent sugar phosphotransferase system IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in phosphoenolpyruvate-dependent sugar phosphotransferase system IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in phosphoenolpyruvate-dependent sugar phosphotransferase system NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    involved_in proton transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    part_of transmembrane transporter complex NAS
    Non-traceable Author Statement
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    putative PTS enzyme IIC component FrwC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      4142530..4143609
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_418384.1 putative PTS enzyme IIC component FrwC [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_418384.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A376JQY0
      Conserved Domains (1) summary
      PRK10478
      Location:1 → 359
      PRK10478; PTS fructose transporter subunit EIIC
    Nucleotide Protein
    Heading Accession and Version

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