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    frwB putative PTS enzyme IIB component FrwB [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 948447, updated on 3-Dec-2024

    Summary

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    Official Symbol
    frwB
    Official Full Name
    putative PTS enzyme IIB component FrwB
    Primary source
    ECOCYC:EG11909
    Locus tag
    b3950
    See related
    ASAP:ABE-0012930
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK3941; yijK
    Summary
    FrwCBD PtsA, a putative PTS permease, belongs to the functional superfamily of the phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system (PTS). [More information is available at EcoCyc: EG11909].
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    Genomic context

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    Sequence:
    NC_000913.3 (4143624..4143944)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene putative PTS multiphosphoryl transfer protein PtsA Neighboring gene putative PTS enzyme IIC component FrwC Neighboring gene putative formate acetyltransferase 2 Neighboring gene putative pyruvate formate-lyase 2 activating enzyme PflC Neighboring gene putative PTS enzyme IIB component FrwD Neighboring gene putative DNA-binding transcriptional regulator YijO

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Novel phosphotransferase system genes revealed by bacterial genome analysis--a gene cluster encoding a unique Enzyme I and the proteins of a fructose-like permease system. Reizer J, et al. Microbiology (Reading), 1995 Apr. PMID 7773398
    2. Analysis of the Escherichia coli genome. IV. DNA sequence of the region from 89.2 to 92.8 minutes. Blattner FR, et al. Nucleic Acids Res, 1993 Nov 25. PMID 8265357, Free PMC Article
    3. Large-scale identification of protein-protein interaction of Escherichia coli K-12. Arifuzzaman M, et al. Genome Res, 2006 May. PMID 16606699, Free PMC Article
    4. The binary protein-protein interaction landscape of Escherichia coli. Rajagopala SV, et al. Nat Biotechnol, 2014 Mar. PMID 24561554, Free PMC Article
    5. Phosphoenolpyruvate:carbohydrate phosphotransferase systems of bacteria. Postma PW, et al. Microbiol Rev, 1993 Sep. PMID 8246840, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in fructose import across plasma membrane NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    involved_in phosphoenolpyruvate-dependent sugar phosphotransferase system IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in phosphoenolpyruvate-dependent sugar phosphotransferase system ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in phosphoenolpyruvate-dependent sugar phosphotransferase system NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of transmembrane transporter complex NAS
    Non-traceable Author Statement
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    putative PTS enzyme IIB component FrwB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      4143624..4143944
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_418385.1 putative PTS enzyme IIB component FrwB [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_418385.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A8S0FGX8
      Conserved Domains (1) summary
      COG1445
      Location:1 → 103
      FrwB; Phosphotransferase system fructose-specific component IIB [Carbohydrate transport and metabolism]
    Nucleotide Protein
    Heading Accession and Version

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