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    dpaA peptidoglycan meso-diaminopimelic acid protein amidase A [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 944910, updated on 3-Dec-2024

    Summary

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    Official Symbol
    dpaA
    Official Full Name
    peptidoglycan meso-diaminopimelic acid protein amidase A
    Primary source
    ECOCYC:G6108
    Locus tag
    b0224
    See related
    ASAP:ABE-0000757
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK0225; ldtF; yafK
    Summary
    The first 19 aa are predicted to be a signal peptide. [More information is available at EcoGene: EG13148]. YafK of enteroaggregative Escherichia coli is required for development of biofilms and for wild-type transcription of genes for type II aggregative adherence fimbriae components . [More information is available at EcoCyc: G6108].
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    Genomic context

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    Sequence:
    NC_000913.3 (245065..245805, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene acyl-CoA dehydrogenase Neighboring gene D-sedoheptulose 7-phosphate isomerase Neighboring gene putative glutamine amidotransferase YafJ Neighboring gene ribosome-dependent mRNA interferase toxin YafQ Neighboring gene antitoxin/DNA-binding transcriptional repressor DinJ

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Roles for Fis and YafK in biofilm formation by enteroaggregative Escherichia coli. Sheikh J, et al. Mol Microbiol, 2001 Sep. PMID 11555281
    2. Cleavage of Braun's lipoprotein Lpp from the bacterial peptidoglycan by a paralog of l,d-transpeptidases, LdtF. Bahadur R, et al. Proc Natl Acad Sci U S A, 2021 May 11. PMID 33941679, Free PMC Article
    3. A functional update of the Escherichia coli K-12 genome. Serres MH, et al. Genome Biol, 2001. PMID 11574054, Free PMC Article
    4. Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110. Hayashi K, et al. Mol Syst Biol, 2006. PMID 16738553, Free PMC Article
    5. The complete genome sequence of Escherichia coli K-12. Blattner FR, et al. Science, 1997 Sep 5. PMID 9278503

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Cleavage of Braun's lipoprotein Lpp from the bacterial peptidoglycan by a paralog of l,d-transpeptidases, LdtF.
      Title: Cleavage of Braun's lipoprotein Lpp from the bacterial peptidoglycan by a paralog of l,d-transpeptidases, LdtF.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    General protein information

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    Preferred Names
    peptidoglycan meso-diaminopimelic acid protein amidase A

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      245065..245805 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_414759.1 peptidoglycan meso-diaminopimelic acid protein amidase A [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_414759.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A765T9T1
      Conserved Domains (1) summary
      COG3034
      Location:1 → 246
      YafK; Murein L,D-transpeptidase YafK [Cell wall/membrane/envelope biogenesis]
    Nucleotide Protein
    Heading Accession and Version

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