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    ybhR ABC exporter membrane subunit YbhR [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 945403, updated on 3-Dec-2024

    Summary

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    Official Symbol
    ybhR
    Official Full Name
    ABC exporter membrane subunit YbhR
    Primary source
    ECOCYC:G6409
    Locus tag
    b0792
    See related
    ASAP:ABE-0002701
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK0781
    Summary
    The putative ybiHybhGFSR operon encodes the YbhG putative membrane fusion protein of efflux pumps. ybhR is paralogous to ybhS, yhhJ, and rbbA. [More information is available at EcoGene: EG13674]. YbhR is a membrane component of a predicted ATP-dependent efflux pump. [More information is available at EcoCyc: G6409].
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    Genomic context

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    Sequence:
    NC_000913.3 (825002..826108, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene PF03706 family inner membrane protein YbhN Neighboring gene cardiolipin synthase B Neighboring gene endonuclease/exonuclease/phosphatase domain-containing protein YbhP Neighboring gene inner membrane protein YbhQ Neighboring gene ABC exporter membrane subunit YbhS Neighboring gene ABC exporter ATP binding subunit YbhF Neighboring gene HlyD_D23 family protein YbhG Neighboring gene DNA-binding transcriptional dual regulator CecR

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A Putative Efflux Transporter of the ABC Family, YbhFSR, in Escherichia coli Functions in Tetracycline Efflux and Na(+)(Li(+))/H(+) Transport. Feng Z, et al. Front Microbiol, 2020. PMID 32390957, Free PMC Article
    2. Systems based mapping demonstrates that recovery from alkylation damage requires DNA repair, RNA processing, and translation associated networks. Rooney JP, et al. Genomics, 2009 Jan. PMID 18824089, Free PMC Article
    3. Over 1000 genes are involved in the DNA damage response of Escherichia coli. Khil PP, et al. Mol Microbiol, 2002 Apr. PMID 11967071
    4. The Escherichia coli ATP-binding cassette (ABC) proteins. Linton KJ, et al. Mol Microbiol, 1998 Apr. PMID 9593292
    5. Transcription factor CecR (YbiH) regulates a set of genes affecting the sensitivity of Escherichia coli against cefoperazone and chloramphenicol. Yamanaka Y, et al. Microbiology (Reading), 2016 Jul. PMID 27112147

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables ABC-type transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables efflux transmembrane transporter activity IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within DNA damage response IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in lithium ion transmembrane transport NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    involved_in sodium ion transmembrane transport NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    involved_in tetracycline transmembrane transport NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within xenobiotic detoxification by transmembrane export across the plasma membrane IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in xenobiotic transmembrane transport NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of ATP-binding cassette (ABC) transporter complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ABC exporter membrane subunit YbhR
    NP_415313.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      825002..826108 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_415313.1 ABC exporter membrane subunit YbhR [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_415313.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A1V2GAY6
      Conserved Domains (1) summary
      pfam12698
      Location:25 → 351
      ABC2_membrane_3; ABC-2 family transporter protein
    Nucleotide Protein
    Heading Accession and Version

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