U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    dhaM dihydroxyacetone kinase subunit M [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 945749, updated on 3-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    dhaM
    Official Full Name
    dihydroxyacetone kinase subunit M
    Primary source
    ECOCYC:EG12399
    Locus tag
    b1198
    See related
    ASAP:ABE-0004024
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    dhaH; ECK1186; ptsD; ycgC
    Summary
    DhaM is phosphorylated by PTS proteins HPr and Protein I. [More information is available at EcoGene: EG12399]. The M subunit is homologous to certain components of PTS: to a domain of EI, to HPr, and to the AB domains of EII. [More information is available at EcoCyc: EG12399].
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    Sequence:
    NC_000913.3 (1247696..1249114, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein YcgY Neighboring gene periplasmic trehalase Neighboring gene dihydroxyacetone kinase subunit L Neighboring gene dihydroxyacetone kinase subunit K

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Analysis and DNA sequence of the osmoregulated treA gene encoding the periplasmic trehalase of Escherichia coli K12. Gutierrez C, et al. Mol Gen Genet, 1989 Jun. PMID 2671658
    2. Phosphoenolpyruvate- and ATP-dependent dihydroxyacetone kinases: covalent substrate-binding and kinetic mechanism. Garcia-Alles LF, et al. Biochemistry, 2004 Oct 19. PMID 15476397
    3. A mechanism of covalent substrate binding in the x-ray structure of subunit K of the Escherichia coli dihydroxyacetone kinase. Siebold C, et al. Proc Natl Acad Sci U S A, 2003 Jul 8. PMID 12813127, Free PMC Article
    4. From ATP as substrate to ADP as coenzyme: functional evolution of the nucleotide binding subunit of dihydroxyacetone kinases. Bächler C, et al. J Biol Chem, 2005 May 6. PMID 15753087
    5. Small substrate, big surprise: fold, function and phylogeny of dihydroxyacetone kinases. Erni B, et al. Cell Mol Life Sci, 2006 Apr. PMID 16505971, Free PMC Article

    See all (17) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

    Go to the top of the page

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables phosphoenolpyruvate-glycerone phosphotransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables phosphoenolpyruvate-glycerone phosphotransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables protein homodimerization activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within DNA damage response IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in carbohydrate phosphorylation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in glycerol catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in phosphoenolpyruvate-dependent sugar phosphotransferase system IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in pyruvate metabolic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of transferase complex IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    dihydroxyacetone kinase subunit M
    NP_415716.4

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      1247696..1249114 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_415716.4 dihydroxyacetone kinase subunit M [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_415716.4

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A1X3JJA4
      Conserved Domains (1) summary
      PRK11377
      Location:1 → 472
      PRK11377; dihydroxyacetone kinase subunit M; Provisional
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.