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    insH5 IS5 family transposase and trans-activator [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 945944, updated on 14-Nov-2024

    Summary

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    Official Symbol
    insH5
    Official Full Name
    IS5 family transposase and trans-activator
    Primary source
    ECOCYC:G6693
    Locus tag
    b1370
    See related
    ASAP:ABE-0004586
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK0261; trs5-5; yi52_5
    Summary
    A single protein sequence is used for InsH although there can be allelic differences at the various IS5 locations. [More information is available at EcoGene: EG60026]. InsH is believed to be the transposase for the insertion sequence element IS5. insH spans the length of IS5 . [More information is available at EcoCyc: G6693].
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    Genomic context

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    Sequence:
    NC_000913.3 (1427746..1428726, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene ParB-like nuclease domain-containing protein YnaK Neighboring gene putative uncharacterized protein YdaY Neighboring gene putative prophage tail length tape measure domain-containing protein YnaA Neighboring gene pseudo Neighboring gene putative prophage side tail fiber protein StfR Neighboring gene putative tail fiber assembly protein TfaR

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. IS5: a mobile enhancer of transcription in Escherichia coli. Schnetz K, et al. Proc Natl Acad Sci U S A, 1992 Feb 15. PMID 1311089, Free PMC Article
    2. Global analysis of candidate genes important for fitness in a competitive biofilm using DNA-array-based transposon mapping. Junker LM, et al. Microbiology (Reading), 2006 Aug. PMID 16849790
    3. Comparison of SDS- and methanol-assisted protein solubilization and digestion methods for Escherichia coli membrane proteome analysis by 2-D LC-MS/MS. Zhang N, et al. Proteomics, 2007 Feb. PMID 17309111
    4. Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110. Hayashi K, et al. Mol Syst Biol, 2006. PMID 16738553, Free PMC Article
    5. The complete genome sequence of Escherichia coli K-12. Blattner FR, et al. Science, 1997 Sep 5. PMID 9278503

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transposase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables transposase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in DNA recombination IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in DNA transposition IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in DNA transposition IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within positive regulation of DNA-templated transcription IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in transposition IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    IS5 family transposase and trans-activator

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      1427746..1428726 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_415888.1 IS5 family transposase and trans-activator [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_415888.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A376WWW9
      Conserved Domains (1) summary
      NF033581
      Location:24 → 313
      transpos_IS5_4; IS5 family transposase
    Nucleotide Protein
    Heading Accession and Version

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