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    ypdE aminopeptidase YpdE [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 946848, updated on 3-Dec-2024

    Summary

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    Official Symbol
    ypdE
    Official Full Name
    aminopeptidase YpdE
    Primary source
    ECOCYC:G7247
    Locus tag
    b2384
    See related
    ASAP:ABE-0007864
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK2380
    Summary
    ypdE, frvX and sgcX are paralogs. [More information is available at EcoGene: EG14152]. YpdE is a metalloendopeptidase with broad-specificity examinopeptidase activity on nonblocked peptides. [More information is available at EcoCyc: G7247].
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    Genomic context

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    Sequence:
    NC_000913.3 (2504510..2505547, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene putative AraC-type DNA-binding transcriptional regulator YpdC Neighboring gene putative PTS multiphosphoryl transfer protein FryA Neighboring gene aminopeptidase YpdF Neighboring gene putative PTS enzyme IIC component FryC

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Characterization of two new aminopeptidases in Escherichia coli. Zheng Y, et al. J Bacteriol, 2005 Jun. PMID 15901689, Free PMC Article
    2. MEROPS: the peptidase database. Rawlings ND, et al. Nucleic Acids Res, 2006 Jan 1. PMID 16381862, Free PMC Article
    3. A functional update of the Escherichia coli K-12 genome. Serres MH, et al. Genome Biol, 2001. PMID 11574054, Free PMC Article
    4. The binary protein-protein interaction landscape of Escherichia coli. Rajagopala SV, et al. Nat Biotechnol, 2014 Mar. PMID 24561554, Free PMC Article
    5. Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110. Hayashi K, et al. Mol Syst Biol, 2006. PMID 16738553, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. YpdE is shown to be a metalloaminopeptidase and has a broad exoaminopeptidase activity
      Title: Characterization of two new aminopeptidases in Escherichia coli.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables aminopeptidase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables aminopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metalloaminopeptidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables metalloaminopeptidase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables metallopeptidase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables metallopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    aminopeptidase YpdE

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      2504510..2505547 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_416885.1 aminopeptidase YpdE [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_416885.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A2X1K3E9
      Conserved Domains (1) summary
      PRK09961
      Location:1 → 344
      PRK09961; aminopeptidase
    Nucleotide Protein
    Heading Accession and Version

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