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    glpR [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 947926, updated on 3-Dec-2024

    Summary

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    Official Symbol
    glpR
    Primary source
    ECOCYC:EG10400
    Locus tag
    b3423
    See related
    ASAP:ABE-0011176
    Gene type
    pseudo
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK3409
    Summary
    The sn-Glycerol-3-phosphate repressor," GlpR, acts as the repressor of the glycerol-3-phosphate regulon, which is organized in different operons . [More information is available at EcoCyc: EG10400].
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    Genomic context

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    Sequence:
    NC_000913.3 (3559848..3560605, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene RNA 3'-terminal phosphate cyclase Neighboring gene RNA-splicing ligase Neighboring gene DNA-binding transcriptional activator RtcR Neighboring gene rhomboid protease GlpG Neighboring gene thiosulfate sulfurtransferase GlpE

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Scalable method to determine mutations that occur during adaptive evolution of Escherichia coli. Raghunathan A, et al. Biotechnol Lett, 2003 Mar. PMID 12882568
    2. Repressor for the sn-glycerol-3-phosphate regulon of Escherichia coli K-12: cloning of the glpR gene and identification of its product. Schweizer H, et al. J Bacteriol, 1985 Feb. PMID 3881401, Free PMC Article
    3. Unexpected presence of defective glpR alleles in various strains of Escherichia coli. Holtman CK, et al. J Bacteriol, 2001 Feb. PMID 11157961, Free PMC Article
    4. Action at a distance for negative control of transcription of the glpD gene encoding sn-glycerol 3-phosphate dehydrogenase of Escherichia coli K-12. Yang B, et al. J Bacteriol, 1996 Dec. PMID 8955388, Free PMC Article
    5. Characterization of the interaction of the glp repressor of Escherichia coli K-12 with single and tandem glp operator variants. Zhao N, et al. J Bacteriol, 1994 Apr. PMID 8157609, Free PMC Article

    See all (29) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Recently identified mutations that are likely to cause loss of function of the glpR and crl genes, which may have serious implications for physiological experiments using the affected strains, are reported.
      Title: Newly identified genetic variations in common Escherichia coli MG1655 stock cultures.
    2. N-terminus verified by Edman degradation on complete protein
      Title: Repressor for the sn-glycerol 3-phosphate regulon of Escherichia coli K-12: primary structure and identification of the DNA-binding domain.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables ligand-activated transcription factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of DNA-templated transcription IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

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