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    tabA DUF386 domain-containing toxin-antitoxin biofilm protein TabA [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 948777, updated on 3-Dec-2024

    Summary

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    Official Symbol
    tabA
    Official Full Name
    DUF386 domain-containing toxin-antitoxin biofilm protein TabA
    Primary source
    ECOCYC:G7883
    Locus tag
    b4252
    See related
    ASAP:ABE-0013921
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK4245; yjgK
    Summary
    yjgK is uniquely induced (3X) in a strain lacking five toxin-antitoxin modules (Kim, 2009). [More information is available at EcoGene: EG12530]. The toxin-antitoxin biofilm protein TabA may decrease biofilm dispersal in response to the combined activity of several toxin-antitoxin (TA) systems. [More information is available at EcoCyc: G7883].
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    Genomic context

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    Sequence:
    NC_000913.3 (4474862..4475314)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene c-di-GMP-binding biofilm dispersal mediator protein Neighboring gene putative transcriptional regulator BdcR Neighboring gene protein YjgL Neighboring gene ornithine carbamoyltransferase ArgI

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Transcriptional regulation of transport and utilization systems for hexuronides, hexuronates and hexonates in gamma purple bacteria. Rodionov DA, et al. Mol Microbiol, 2000 Nov. PMID 11115104
    2. Toxin-antitoxin systems in Escherichia coli influence biofilm formation through YjgK (TabA) and fimbriae. Kim Y, et al. J Bacteriol, 2009 Feb. PMID 19060153, Free PMC Article
    3. Crystal structure of the bacterial YhcH protein indicates a role in sialic acid catabolism. Teplyakov A, et al. J Bacteriol, 2005 Aug. PMID 16077096, Free PMC Article
    4. Enrichment of low abundance proteins of Escherichia coli by hydroxyapatite chromatography. Fountoulakis M, et al. Electrophoresis, 1999 Aug. PMID 10493123
    5. Analysis of the Escherichia coli genome VI: DNA sequence of the region from 92.8 through 100 minutes. Burland V, et al. Nucleic Acids Res, 1995 Jun 25. PMID 7610040, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Process Evidence Code Pubs
    involved_in single-species biofilm formation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within single-species biofilm formation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    DUF386 domain-containing toxin-antitoxin biofilm protein TabA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      4474862..4475314
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_418673.4 DUF386 domain-containing toxin-antitoxin biofilm protein TabA [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_418673.4

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A8T5YDR7
      Conserved Domains (1) summary
      TIGR00022
      Location:1 → 139
      TIGR00022; YhcH/YjgK/YiaL family protein
    Nucleotide Protein
    Heading Accession and Version

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