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    ycaL periplasmic protease YcaL [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 945534, updated on 3-Dec-2024

    Summary

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    Official Symbol
    ycaL
    Official Full Name
    periplasmic protease YcaL
    Primary source
    ECOCYC:G6470
    Locus tag
    b0909
    See related
    ASAP:ABE-0003098
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK0900
    Summary
    Gene disruption does not cause growth defect, unpublished data, Y. [More information is available at EcoGene: EG13133].
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    Genomic context

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    Sequence:
    NC_000913.3 (960264..961028)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene phosphoserine/phosphohydroxythreonine aminotransferase Neighboring gene 3-phosphoshikimate 1-carboxyvinyltransferase Neighboring gene cytidylate kinase Neighboring gene 30S ribosomal subunit protein S1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The cmk gene encoding cytidine monophosphate kinase is located in the rpsA operon and is required for normal replication rate in Escherichia coli. Fricke J, et al. J Bacteriol, 1995 Feb. PMID 7836281, Free PMC Article
    2. Proteolytic activity of HtpX, a membrane-bound and stress-controlled protease from Escherichia coli. Sakoh M, et al. J Biol Chem, 2005 Sep 30. PMID 16076848
    3. Genetic analysis of 15 protein folding factors and proteases of the Escherichia coli cell envelope. Weski J, et al. J Bacteriol, 2012 Jun. PMID 22505681, Free PMC Article
    4. Prediction of lipoprotein signal peptides in Gram-negative bacteria. Juncker AS, et al. Protein Sci, 2003 Aug. PMID 12876315, Free PMC Article
    5. Fine-tuning the prediction of sequences cleaved by signal peptidase II: a curated set of proven and predicted lipoproteins of Escherichia coli K-12. Gonnet P, et al. Proteomics, 2004 Jun. PMID 15174130

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metalloendopeptidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables metalloendopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metallopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metallopeptidase activity TAS
    Traceable Author Statement
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within proteolysis involved in protein catabolic process EXP
    Inferred from Experiment
    more info
    		 PubMed 
    involved_in proteolysis involved in protein catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    periplasmic protease YcaL

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      960264..961028
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_415429.2 periplasmic protease YcaL [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_415429.2

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A2X1J093
      Conserved Domains (1) summary
      cd07334
      Location:34 → 249
      M48C_loiP_like; Peptidase M48C Ste24p loiP-like, integral membrane protein
    Nucleotide Protein
    Heading Accession and Version

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