U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    patD gamma-aminobutyraldehyde dehydrogenase [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 945876, updated on 3-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    patD
    Official Full Name
    gamma-aminobutyraldehyde dehydrogenase
    Primary source
    ECOCYC:G6755
    Locus tag
    b1444
    See related
    ASAP:ABE-0004813
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK1438; prr; ydcW
    Summary
    YdcW is the Prr gamma-aminobutyraldehyde dehydrogenase; PatA(YgjG) couped with Prr(YdcW) convert putrescine to gamma-aminobutyric acid in addition to the Puu pathway (Reitzer, 2003; Samsonova, 2005). [More information is available at EcoGene: EG13766]. aminobutyraldehyde dehydrogenase is the second enzyme in a putrescine degradation pathway . [More information is available at EcoCyc: G6755].
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    Sequence:
    NC_000913.3 (1515578..1517002)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene putative ABC transporter ATP-binding protein YdcT Neighboring gene putative ABC transporter membrane subunit YdcU Neighboring gene putative ABC transporter membrane subunit YdcV Neighboring gene uncharacterized protein YncL Neighboring gene orphan toxin OrtT

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Properties of gamma-aminobutyraldehyde dehydrogenase from Escherichia coli. Prieto MI, et al. Biochimie, 1987 Nov-Dec. PMID 3129020
    2. Control of utilization of L-arginine, L-ornithine, agmatine, and putrescine as nitrogen sources in Escherichia coli K-12. Shaibe E, et al. J Bacteriol, 1985 Sep. PMID 3897202, Free PMC Article
    3. A pathway for putrescine catabolism in Escherichia coli. Prieto-Santos MI, et al. Biochim Biophys Acta, 1986 Feb 19. PMID 3510672
    4. Metabolic pathway for the utilization of L-arginine, L-ornithine, agmatine, and putrescine as nitrogen sources in Escherichia coli K-12. Shaibe E, et al. J Bacteriol, 1985 Sep. PMID 3897201, Free PMC Article
    5. Nitrogen assimilation and global regulation in Escherichia coli. Reitzer L. Annu Rev Microbiol, 2003. PMID 12730324

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. identification as gamma-aminobutyraldehyde dehydrogenase
      Title: Identification of Escherichia coli K12 YdcW protein as a gamma-aminobutyraldehyde dehydrogenase.
    Submit: New GeneRIF Correction

    Pathways from PubChem

    Go to the top of the page

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables NAD binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables aldehyde dehydrogenase (NAD+) activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables aldehyde dehydrogenase [NAD(P)+] activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables aminobutyraldehyde dehydrogenase (NAD+) activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables aminobutyraldehyde dehydrogenase (NAD+) activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables aminobutyraldehyde dehydrogenase (NAD+) activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables identical protein binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in L-lysine catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within protein homotetramerization IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within putrescine catabolic process EXP
    Inferred from Experiment
    more info
    		 PubMed 
    involved_in putrescine catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within putrescine catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of protein-containing complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    gamma-aminobutyraldehyde dehydrogenase
    NP_415961.1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      1515578..1517002
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_415961.1 gamma-aminobutyraldehyde dehydrogenase [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_415961.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A8S7TAI6
      Conserved Domains (1) summary
      TIGR03374
      Location:2 → 473
      ABALDH; 1-pyrroline dehydrogenase
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.