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    exoX exonuclease X [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 946361, updated on 3-Dec-2024

    Summary

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    Official Symbol
    exoX
    Official Full Name
    exonuclease X
    Primary source
    ECOCYC:G7016
    Locus tag
    b1844
    See related
    ASAP:ABE-0006131
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK1845; yobC
    Summary
    Exonuclease X is a DNA repair enzyme involved in mismatch repair, and is able to degrade both single-stranded and duplex DNA . [More information is available at EcoCyc: G7016].
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    Genomic context

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    Sequence:
    NC_000913.3 (1926120..1926782)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene DNA polymerase III subunit theta Neighboring gene putative carbon-nitrogen hydrolase family protein YobB Neighboring gene oligopeptidase B Neighboring gene DUF533 domain-containing inner membrane protein YebE Neighboring gene secreted protein YebF

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Functional interaction between MutL and 3'-5' exonuclease X in Escherichia coli. Cheng F, et al. Arch Biochem Biophys, 2010 Oct 1. PMID 20638361
    2. A role for single-stranded exonucleases in the use of DNA as a nutrient. Palchevskiy V, et al. J Bacteriol, 2009 Jun. PMID 19329645, Free PMC Article
    3. Stabilization of perfect and imperfect tandem repeats by single-strand DNA exonucleases. Feschenko VV, et al. Proc Natl Acad Sci U S A, 2003 Feb 4. PMID 12538867, Free PMC Article
    4. RecA-independent recombination is efficient but limited by exonucleases. Dutra BE, et al. Proc Natl Acad Sci U S A, 2007 Jan 2. PMID 17182742, Free PMC Article
    5. Redundant exonuclease involvement in Escherichia coli methyl-directed mismatch repair. Viswanathan M, et al. J Biol Chem, 2001 Aug 17. PMID 11418610

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables 3'-5' exonuclease activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables 3'-5' exonuclease activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables exonuclease activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in DNA metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in DNA repair IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in DNA replication proofreading IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within mismatch repair IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    exonuclease X

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      1926120..1926782
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_416358.1 exonuclease X [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_416358.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A376K135
      Conserved Domains (1) summary
      PRK07983
      Location:1 → 219
      PRK07983; exodeoxyribonuclease X; Provisional
    Nucleotide Protein
    Heading Accession and Version

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