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    oxc oxalyl-CoA decarboxylase [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 946845, updated on 3-Dec-2024

    Summary

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    Official Symbol
    oxc
    Official Full Name
    oxalyl-CoA decarboxylase
    Primary source
    ECOCYC:G7236
    Locus tag
    b2373
    See related
    ASAP:ABE-0007826
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK2369; yfdU
    Summary
    Orthologous to O. formigenes Oxc. [More information is available at EcoGene: EG14143].
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    Genomic context

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    Sequence:
    NC_000913.3 (2490256..2491950, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene acetyl-CoA:oxalate CoA-transferase Neighboring gene putative transport protein YfdV Neighboring gene formyl-CoA transferase Neighboring gene protein YfdX

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. New insights into structure-function relationships of oxalyl CoA decarboxylase from Escherichia coli. Werther T, et al. FEBS J, 2010 Jun. PMID 20553497
    2. Molecular cloning, DNA sequence, and gene expression of the oxalyl-coenzyme A decarboxylase gene, oxc, from the bacterium Oxalobacter formigenes. Lung HY, et al. J Bacteriol, 1994 Apr. PMID 8157618, Free PMC Article
    3. YfdW and YfdU are required for oxalate-induced acid tolerance in Escherichia coli K-12. Fontenot EM, et al. J Bacteriol, 2013 Apr. PMID 23335415, Free PMC Article
    4. Escherichia coli gene expression responsive to levels of the response regulator EvgA. Masuda N, et al. J Bacteriol, 2002 Nov. PMID 12399493, Free PMC Article
    5. The crystal structure of the Escherichia coli YfdW gene product reveals a new fold of two interlaced rings identifying a wide family of CoA transferases. Gruez A, et al. J Biol Chem, 2003 Sep 5. PMID 12844490

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables ADP binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables carboxy-lyase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables identical protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables magnesium ion binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables magnesium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxalyl-CoA decarboxylase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables oxalyl-CoA decarboxylase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables oxalyl-CoA decarboxylase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables thiamine pyrophosphate binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables thiamine pyrophosphate binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables thiamine pyrophosphate binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in carboxylic acid metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within cellular response to acidic pH IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in fatty acid alpha-oxidation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in oxalate catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in oxalate catabolic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in oxalate catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    oxalyl-CoA decarboxylase
    NP_416874.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      2490256..2491950 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_416874.1 oxalyl-CoA decarboxylase [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_416874.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A6N8R271, A0A8S7EHK5
      Conserved Domains (1) summary
      TIGR03254
      Location:6 → 559
      oxalate_oxc; oxalyl-CoA decarboxylase
    Nucleotide Protein
    Heading Accession and Version

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