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    cysZ sulfate:H(+) symporter [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 946875, updated on 3-Dec-2024

    Summary

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    Official Symbol
    cysZ
    Official Full Name
    sulfate:H(+) symporter
    Primary source
    ECOCYC:EG10003
    Locus tag
    b2413
    See related
    ASAP:ABE-0007953
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK2408
    Summary
    A cysZ mutant is deficient in sulfate assimilation . [More information is available at EcoCyc: EG10003].
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    Genomic context

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    Sequence:
    NC_000913.3 (2531463..2532224)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene DNA ligase Neighboring gene cell division protein ZipA Neighboring gene cysteine synthase A Neighboring gene phosphocarrier protein HPr

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Escherichia coli CysZ is a pH dependent sulfate transporter that can be inhibited by sulfite. Zhang L, et al. Biochim Biophys Acta, 2014 Jul. PMID 24657232
    2. Phylogeny of metabolic pathways: O-acetylserine sulphydrylase A is homologous to the tryptophan synthase beta subunit. Levy S, et al. Mol Microbiol, 1988 Nov. PMID 3062311
    3. DNA sequences of the cysK regions of Salmonella typhimurium and Escherichia coli and linkage of the cysK regions to ptsH. Byrne CR, et al. J Bacteriol, 1988 Jul. PMID 3290198, Free PMC Article
    4. Direct binding of FtsZ to ZipA, an essential component of the septal ring structure that mediates cell division in E. coli. Hale CA, et al. Cell, 1997 Jan 24. PMID 9008158
    5. Two separate genes involved in sulphate transport in Escherichia coli K12. Parra F, et al. J Gen Microbiol, 1983 Feb. PMID 6341507

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables high-affinity sulfate:proton symporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables high-affinity sulfate:proton symporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables sulfate transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables sulfate transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in cysteine biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within cysteine biosynthetic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in cysteine biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in proton transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in sulfate assimilation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in sulfate assimilation IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within sulfate assimilation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within sulfate transmembrane transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in sulfate transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    sulfate:H(+) symporter

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      2531463..2532224
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_416908.1 sulfate:H(+) symporter [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_416908.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A5C9AH02
      Conserved Domains (1) summary
      PRK04949
      Location:3 → 253
      PRK04949; putative sulfate transport protein CysZ; Validated
    Nucleotide Protein
    Heading Accession and Version

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