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    ucpA oxidoreductase UcpA [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 946898, updated on 17-Dec-2024

    Summary

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    Official Symbol
    ucpA
    Official Full Name
    oxidoreductase UcpA
    Primary source
    ECOCYC:EG12133
    Locus tag
    b2426
    See related
    ASAP:ABE-0007996
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK2421; yfeF
    Summary
    Based on sequence similarity, UcpA is predicted to be an acetoin dehydrogenase (diacetyl reductase) . [More information is available at EcoCyc: EG12133].
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    Genomic context

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    Sequence:
    NC_000913.3 (2543832..2544623, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene sulfate/thiosulfate ABC transporter inner membrane subunit CysW Neighboring gene sulfate/thiosulfate ABC transporter inner membrane subunit CysU Neighboring gene thiosulfate/sulfate ABC transporter periplasmic binding protein CysP Neighboring gene DNA-binding transcriptional dual regulator MurR Neighboring gene N-acetylmuramic acid 6-phosphate etherase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Selection of an endogenous 2,3-butanediol pathway in Escherichia coli by fermentative redox balance. Liang K, et al. Metab Eng, 2017 Jan. PMID 27931827
    2. Increased furan tolerance in Escherichia coli due to a cryptic ucpA gene. Wang X, et al. Appl Environ Microbiol, 2012 Apr. PMID 22267665, Free PMC Article
    3. Sulfate and thiosulfate transport in Escherichia coli K-12: identification of a gene encoding a novel protein involved in thiosulfate binding. Hryniewicz M, et al. J Bacteriol, 1990 Jun. PMID 2188959, Free PMC Article
    4. An expanded genome-scale model of Escherichia coli K-12 (iJR904 GSM/GPR). Reed JL, et al. Genome Biol, 2003. PMID 12952533, Free PMC Article
    5. Characterization of the Escherichia coli gene encoding a new member of the short-chain dehydrogenase/reductase (SDR) family. Sirko A, et al. Acta Biochim Pol, 1997. PMID 9241368

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables diacetyl reductase ((S)-acetoin forming) (NAD+) activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    oxidoreductase UcpA
    NP_416921.4

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      2543832..2544623 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_416921.4 oxidoreductase UcpA [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_416921.4

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A2H4TWW0
      Conserved Domains (1) summary
      PRK08226
      Location:1 → 263
      PRK08226; SDR family oxidoreductase UcpA
    Nucleotide Protein
    Heading Accession and Version

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