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    ppdA prepilin-type N-terminal cleavage/methylation domain-containing protein PpdA [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 945393, updated on 3-Dec-2024

    Summary

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    Official Symbol
    ppdA
    Official Full Name
    prepilin-type N-terminal cleavage/methylation domain-containing protein PpdA
    Primary source
    ECOCYC:EG12081
    Locus tag
    b2826
    See related
    ASAP:ABE-0009266
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK2822
    Summary
    Overexpression causes abnormal biofilm architecture. ppdA is predicted to have a CRP-S promoter co-regulated by both Crp and Sxy (Cameron, 2006). [More information is available at EcoGene: EG12081]. A ppdAB mutant does not exhibit defects in chemotaxis or flagellar motility . [More information is available at EcoCyc: EG12081].
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    Genomic context

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    Sequence:
    NC_000913.3 (2963707..2964177, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene exodeoxyribonuclease V subunit RecC Neighboring gene prepilin-type N-terminal cleavage/methylation domain-containing protein PpdC Neighboring gene DUF2509 domain-containing protein YgdB Neighboring gene prepilin-type N-terminal cleavage/methylation domain-containing protein PpdB Neighboring gene thymidylate synthase Neighboring gene phosphatidylglycerol--prolipoprotein diacylglyceryl transferase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Novel sigmaF-dependent genes of Escherichia coli found using a specified promoter consensus. Park K, et al. FEMS Microbiol Lett, 2001 Aug 21. PMID 11520622
    2. Common components in the assembly of type 4 fimbriae, DNA transfer systems, filamentous phage and protein-secretion apparatus: a general system for the formation of surface-associated protein complexes. Hobbs M, et al. Mol Microbiol, 1993 Oct. PMID 7934814
    3. Complete nucleotide sequence of the Escherichia coli recC gene and of the thyA-recC intergenic region. Finch PW, et al. Nucleic Acids Res, 1986 Jun 11. PMID 3520484, Free PMC Article
    4. Non-canonical CRP sites control competence regulons in Escherichia coli and many other gamma-proteobacteria. Cameron AD, et al. Nucleic Acids Res, 2006. PMID 17068078, Free PMC Article
    5. Comparison of the PhoPQ regulon in Escherichia coli and Salmonella typhimurium. Monsieurs P, et al. J Mol Evol, 2005 Apr. PMID 15883881

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    prepilin-type N-terminal cleavage/methylation domain-containing protein PpdA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      2963707..2964177 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_417303.1 prepilin-type N-terminal cleavage/methylation domain-containing protein PpdA [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_417303.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A376FVI3, A0A6D0IK53, A0A8S7EIC8
      Conserved Domains (1) summary
      PRK10506
      Location:1 → 156
      PRK10506; prepilin peptidase-dependent protein
    Nucleotide Protein
    Heading Accession and Version

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