U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    lysR DNA-binding transcriptional dual regulator LysR [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 947311, updated on 17-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    lysR
    Official Full Name
    DNA-binding transcriptional dual regulator LysR
    Primary source
    ECOCYC:EG10551
    Locus tag
    b2839
    See related
    ASAP:ABE-0009313
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK2837
    Summary
    "Lysine Regulator," LysR, is negatively autoregulated and coordinately activates transcription of the divergent gene which encodes the enzyme that catalyzes the last step in lysine biosynthesis . [More information is available at EcoCyc: EG10551].
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    Sequence:
    NC_000913.3 (2979021..2979956)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene DNA-binding transcriptional dual regulator GalR Neighboring gene diaminopimelate decarboxylase Neighboring gene amino acid racemase YgeA Neighboring gene arabinose:H(+) symporter Neighboring gene putative 2-keto-3-deoxy-D-gluconate dehydrogenase

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Specificity of the E. coli LysR-type transcriptional regulators. Knapp GS, et al. PLoS One, 2010 Dec 20. PMID 21187915, Free PMC Article
    2. Regulatory pattern of the Escherichia coli lysA gene: expression of chromosomal lysA-lacZ fusions. Stragier P, et al. J Bacteriol, 1983 Dec. PMID 6417111, Free PMC Article
    3. Regulation of diaminopimelate decarboxylase synthesis in Escherichia coli. I. Identification of a lysR gene encoding an activator of the lysA gene. Stragier P, et al. J Mol Biol, 1983 Aug 5. PMID 6411928
    4. Regulation of diaminopimelate decarboxylase synthesis in Escherichia coli. II. Nucleotide sequence of the lysA gene and its regulatory region. Stragier P, et al. J Mol Biol, 1983 Aug 5. PMID 6350601
    5. A large family of bacterial activator proteins. Henikoff S, et al. Proc Natl Acad Sci U S A, 1988 Sep. PMID 3413113, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in lysine biosynthetic process via diaminopimelate IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within lysine biosynthetic process via diaminopimelate IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in lysine biosynthetic process via diaminopimelate IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in positive regulation of gene expression IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within positive regulation of gene expression IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    DNA-binding transcriptional dual regulator LysR

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      2979021..2979956
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_417316.1 DNA-binding transcriptional dual regulator LysR [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_417316.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A2H4TVI6
      Conserved Domains (1) summary
      PRK11013
      Location:1 → 309
      PRK11013; DNA-binding transcriptional regulator LysR; Provisional
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.