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    sgbU putative L-xylulose 5-phosphate 3-epimerase [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 948100, updated on 3-Dec-2024

    Summary

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    Official Symbol
    sgbU
    Official Full Name
    putative L-xylulose 5-phosphate 3-epimerase
    Primary source
    ECOCYC:EG12286
    Locus tag
    b3582
    See related
    ASAP:ABE-0011700
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK3571; yiaR
    Summary
    YiaQ is possibly involved in the utilization of L-dehydroascorbate (2,3-diketo-L-gulonate) (Yew, 2002). [More information is available at EcoGene: EG12286]. SgbU appears to be required for the utilization of L-lyxose . [More information is available at EcoCyc: EG12286].
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    Genomic context

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    Sequence:
    NC_000913.3 (3749232..3750092)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene 2,3-diketo-L-gulonate:Na(+) symporter - periplasmic binding protein Neighboring gene L-xylulose kinase Neighboring gene 3-keto-L-gulonate-6-phosphate decarboxylase SgbH Neighboring gene L-ribulose-5-phosphate 4-epimerase SgbE Neighboring gene pseudo Neighboring gene pseudo

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Transporter's evolution and carbohydrate metabolic clusters. Plantinga TH, et al. Trends Microbiol, 2004 Jan. PMID 14700544
    2. Aerobic L-ascorbate metabolism and associated oxidative stress in Escherichia coli. Campos E, et al. Microbiology (Reading), 2007 Oct. PMID 17906139
    3. A rare 920-kilobase chromosomal inversion mediated by IS1 transposition causes constitutive expression of the yiaK-S operon for carbohydrate utilization in Escherichia coli. Badía J, et al. J Biol Chem, 1998 Apr 3. PMID 9525947
    4. The gene yjfQ encodes the repressor of the yjfR-X regulon (ula), which is involved in L-ascorbate metabolism in Escherichia coli. Campos E, et al. J Bacteriol, 2002 Nov. PMID 12374842, Free PMC Article
    5. Regulation of expression of the yiaKLMNOPQRS operon for carbohydrate utilization in Escherichia coli: involvement of the main transcriptional factors. Ibañez E, et al. J Bacteriol, 2000 Aug. PMID 10913096, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables L-ribulose-5-phosphate 3-epimerase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables L-ribulose-5-phosphate 3-epimerase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables L-ribulose-5-phosphate 3-epimerase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables intramolecular oxidoreductase activity, interconverting aldoses and ketoses IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables isomerase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in DNA repair IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in L-ascorbic acid metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within L-lyxose metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in carbohydrate metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    putative L-xylulose 5-phosphate 3-epimerase
    NP_418039.2

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      3749232..3750092
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_418039.2 putative L-xylulose 5-phosphate 3-epimerase [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_418039.2

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A6M9WYU2
      Conserved Domains (1) summary
      PRK13210
      Location:2 → 284
      PRK13210; L-ribulose-5-phosphate 3-epimerase
    Nucleotide Protein
    Heading Accession and Version

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