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    waaO UDP-D-glucose:(glucosyl)LPS alpha-1,3-glucosyltransferase [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 948143, updated on 3-Dec-2024

    Summary

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    Official Symbol
    waaO
    Official Full Name
    UDP-D-glucose:(glucosyl)LPS alpha-1,3-glucosyltransferase
    Primary source
    ECOCYC:EG11352
    Locus tag
    b3627
    See related
    ASAP:ABE-0011860
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK3617; rfaI; waaI
    Summary
    The lipopolysaccharide of Escherichia coli K-12 consists of two major components: the hydrophobic lipid A moiety inserted into the outer membrane and the phosphorylated core oligosaccharide . [More information is available at EcoCyc: EG11352].
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    Genomic context

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    Sequence:
    NC_000913.3 (3802039..3803058, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene lipopolysaccharide core heptose (II) kinase Neighboring gene UDP-glucose:(glucosyl)LPS alpha-1,2-glucosyltransferase Neighboring gene UDP-D-galactose:(glucosyl)lipopolysaccharide-1,6-D-galactosyltransferase Neighboring gene lipopolysaccharide core biosynthesis protein WaaS

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Conserved structural regions involved in the catalytic mechanism of Escherichia coli K-12 WaaO (RfaI). Shibayama K, et al. J Bacteriol, 1998 Oct. PMID 9765561, Free PMC Article
    2. Cloning of genes for bacterial glycosyltransferases. I. Selection of hybrid plasmids carrying genes for two glucosyltransferases. Creeger ES, et al. J Biol Chem, 1979 Feb 10. PMID 368061
    3. Cloning genes for bacterial glycosyltransferases. Creeger ES, et al. Methods Enzymol, 1982. PMID 6212748
    4. Identification of bacteriophage K20 binding regions of OmpF and lipopolysaccharide in Escherichia coli K-12. Traurig M, et al. FEMS Microbiol Lett, 1999 Dec 1. PMID 10564794
    5. Regulation of membrane glycosyltransferases by the sfrB and rfaH genes of Escherichia coli and Salmonella typhimurium. Creeger ES, et al. J Biol Chem, 1984 Mar 10. PMID 6230355

    See all (24) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables glycosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables lipopolysaccharide 3-alpha-galactosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables lipopolysaccharide glucosyltransferase II activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables lipopolysaccharide glucosyltransferase II activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in lipopolysaccharide biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in lipopolysaccharide core region biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within lipopolysaccharide core region biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    UDP-D-glucose:(glucosyl)LPS alpha-1,3-glucosyltransferase
    NP_418084.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      3802039..3803058 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_418084.1 UDP-D-glucose:(glucosyl)LPS alpha-1,3-glucosyltransferase [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_418084.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A8S0FDR5
      Conserved Domains (1) summary
      PRK15171
      Location:4 → 338
      PRK15171; lipopolysaccharide 3-alpha-galactosyltransferase
    Nucleotide Protein
    Heading Accession and Version

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