U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    fabR DNA-binding transcriptional repressor FabR [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 948460, updated on 3-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    fabR
    Official Full Name
    DNA-binding transcriptional repressor FabR
    Primary source
    ECOCYC:EG11394
    Locus tag
    b3963
    See related
    ASAP:ABE-0012979
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK3955; yijC
    Summary
    TetR family. [More information is available at EcoGene: EG11394]. FabR, "fatty acid biosynthesis regulator," regulates the expression of genes involved in the synthesis of unsaturated fatty acids . [More information is available at EcoCyc: EG11394].
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    Sequence:
    NC_000913.3 (4161067..4161771)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene DNA-binding transcriptional dual regulator OxyR Neighboring gene soluble pyridine nucleotide transhydrogenase Neighboring gene DUF1422 domain-containing inner membrane protein YijD Neighboring gene tRNA m(5)U54 methyltransferase Neighboring gene cobalamin outer membrane transporter Neighboring gene glutamate racemase

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Physical properties of membrane lipids: biological relevance and regulation. Cronan JE Jr, et al. Bacteriol Rev, 1975 Sep. PMID 1100043, Free PMC Article
    2. Transcriptional regulation of membrane lipid homeostasis in Escherichia coli. Zhu K, et al. J Biol Chem, 2009 Dec 11. PMID 19854834, Free PMC Article
    3. Mechanistic diversity and regulation of Type II fatty acid synthesis. Marrakchi H, et al. Biochem Soc Trans, 2002 Nov. PMID 12440970
    4. The Pfam protein families database. Bateman A, et al. Nucleic Acids Res, 2000 Jan 1. PMID 10592242, Free PMC Article
    5. Regulation of fatty acid metabolism in bacteria. Fujita Y, et al. Mol Microbiol, 2007 Nov. PMID 17919287

    See all (17) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

    Go to the top of the page

    General gene information

    Go to the top of the page Help

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables DNA-binding transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in fatty acid biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in fatty acid metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within negative regulation of DNA-templated transcription IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in negative regulation of fatty acid biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    DNA-binding transcriptional repressor FabR

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      4161067..4161771
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_418398.3 DNA-binding transcriptional repressor FabR [Escherichia coli str. K-12 substr. MG1655]

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A0D6HJK5, A0A0E2LD18, A0A0H3ENR8, A0A0K4WZZ8, A0A7U9IUA8, A0A979H3Z8, B7MIA3, B7MR91, S1NUE8
      Conserved Domains (1) summary
      PRK11202
      Location:20 → 219
      PRK11202; HTH-type transcriptional repressor FabR
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.