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    creB DNA-binding transcriptional regulator CreB [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 948922, updated on 3-Dec-2024

    Summary

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    Official Symbol
    creB
    Official Full Name
    DNA-binding transcriptional regulator CreB
    Primary source
    ECOCYC:EG11218
    Locus tag
    b4398
    See related
    ASAP:ABE-0014428
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK4390; ORF2; yjjE
    Summary
    The transcriptional regulatory protein CreB is a member of the CreC/CreB two-component regulatory system. [More information is available at EcoCyc: EG11218].
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    Genomic context

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    Sequence:
    NC_000913.3 (4636007..4636696)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene putative phosphatase Neighboring gene DNA-binding transcriptional dual regulator Rob Neighboring gene PF05981 family protein CreA Neighboring gene sensory histidine kinase CreC Neighboring gene putative inner membrane protein CreD Neighboring gene DNA-binding transcriptional dual regulator ArcA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Metabolic flux analysis of Escherichia coli creB and arcA mutants reveals shared control of carbon catabolism under microaerobic growth conditions. Nikel PI, et al. J Bacteriol, 2009 Sep. PMID 19561129, Free PMC Article
    2. Is cross regulation by phosphorylation of two-component response regulator proteins important in bacteria? Wanner BL. J Bacteriol, 1992 Apr. PMID 1551826, Free PMC Article
    3. Cross talk to the phosphate regulon of Escherichia coli by PhoM protein: PhoM is a histidine protein kinase and catalyzes phosphorylation of PhoB and PhoM-open reading frame 2. Amemura M, et al. J Bacteriol, 1990 Nov. PMID 2228961, Free PMC Article
    4. Nucleotide sequence of the phoM region of Escherichia coli: four open reading frames may constitute an operon. Amemura M, et al. J Bacteriol, 1986 Oct. PMID 3531171, Free PMC Article
    5. Bacterial sensor kinase/response regulator systems: an introduction. Saier MH Jr. Res Microbiol, 1994 Jun-Aug. PMID 7855419

    See all (24) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables cis-regulatory region sequence-specific DNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables identical protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables phosphorelay response regulator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables transcription cis-regulatory region binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in phosphorelay signal transduction system IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within positive regulation of DNA-templated transcription IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of DNA-templated transcription IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of protein-DNA complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    DNA-binding transcriptional regulator CreB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      4636007..4636696
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_418815.1 DNA-binding transcriptional regulator CreB [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_418815.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A6C9JYE8
      Conserved Domains (1) summary
      PRK11083
      Location:1 → 228
      PRK11083; DNA-binding response regulator CreB; Provisional
    Nucleotide Protein
    Heading Accession and Version

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