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    uxaB tagaturonate reductase [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 945542, updated on 17-Dec-2024

    Summary

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    Official Symbol
    uxaB
    Official Full Name
    tagaturonate reductase
    Primary source
    ECOCYC:EG11065
    Locus tag
    b1521
    See related
    ASAP:ABE-0005076
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK1514
    Summary
    ExuR regulon. [More information is available at EcoGene: EG11065]. Altronate oxidoreductase is the second enzyme of the galacturonate catabolism pathway, catalyzing the reversible NADH-dependent reduction of D-tagaturonate to D-altronate . [More information is available at EcoCyc: EG11065].
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    Genomic context

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    Sequence:
    NC_000913.3 (1609229..1610680, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene trans-aconitate 2-methyltransferase Neighboring gene PF01062 family inner membrane protein YneE Neighboring gene putative diguanylate cyclase DgcF Neighboring gene DUF4186 domain-containing protein YneG Neighboring gene glutaminase 2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Determination of the transcription direction of the uxaB gene, in Escherichia coli K12. Hugouvieux-Cotte-Pattat N, et al. Mol Gen Genet, 1983. PMID 6343794
    2. [D-altronate: NAD-oxidoreductase in Escherichia coli K12. Purification, properties, and specificity]. Portalier RC, et al. Eur J Biochem, 1972 Mar 15. PMID 4402917
    3. [D-altronate: NAD-oxidoreductase from Escherichia coli K12. Kinetic studies]. Portalier RC. Eur J Biochem, 1972 Oct. PMID 4351434
    4. Uronic acid metabolism in bacteria. II. Purification and properties of D-altronic acid and D-mannonic acid dehydrogenases in Escherichia coli. HICKMAN J, et al. J Biol Chem, 1960 Jun. PMID 14401695
    5. D-Mannonate and D-altronate-NAD dehydrogenases from Escherichia coli. Portalier R, et al. Methods Enzymol, 1982. PMID 6755169

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. N-terminus verified by Edman degradation on complete protein
      Title: A DNA sequence containing the control sites for the uxaB gene of Escherichia coli.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables mannitol-1-phosphate 5-dehydrogenase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables tagaturonate reductase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables tagaturonate reductase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables tagaturonate reductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in D-galacturonate catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within D-galacturonate catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in mannitol catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    tagaturonate reductase
    YP_025302.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      1609229..1610680 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. YP_025302.1 tagaturonate reductase [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for YP_025302.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A7D7KJY6
      Conserved Domains (1) summary
      PRK03643
      Location:1 → 472
      PRK03643; tagaturonate reductase
    Nucleotide Protein
    Heading Accession and Version

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