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    kduD putative 2-keto-3-deoxy-D-gluconate dehydrogenase [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 947323, updated on 17-Dec-2024

    Summary

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    Official Symbol
    kduD
    Official Full Name
    putative 2-keto-3-deoxy-D-gluconate dehydrogenase
    Primary source
    ECOCYC:EG12361
    Locus tag
    b2842
    See related
    ASAP:ABE-0009330
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK2840; ygeC; yqeD
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    Genomic context

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    Sequence:
    NC_000913.3 (2982497..2983258, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene DNA-binding transcriptional dual regulator LysR Neighboring gene amino acid racemase YgeA Neighboring gene arabinose:H(+) symporter Neighboring gene 5-dehydro-4-deoxy-D-glucuronate isomerase Neighboring gene putative acyltransferase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Selection of thiol- and disulfide-containing proteins of Escherichia coli on activated thiol-Sepharose. Hu W, et al. Anal Biochem, 2010 Mar 15. PMID 19903445
    2. Biocatalytic synthesis of 4-pregnen-20,21-diol-3-one, a selective inhibitor of human 5alpha-reductase type II. Hannemann F, et al. J Enzyme Inhib Med Chem, 2007 Oct. PMID 18035825
    3. The cloning, DNA sequence, and overexpression of the gene araE coding for arabinose-proton symport in Escherichia coli K12. Maiden MC, et al. J Biol Chem, 1988 Jun 15. PMID 2836407
    4. Comparative genomics of the KdgR regulon in Erwinia chrysanthemi 3937 and other gamma-proteobacteria. Rodionov DA, et al. Microbiology (Reading), 2004 Nov. PMID 15528647
    5. Regulation of pectinolysis in Erwinia chrysanthemi. Hugouvieux-Cotte-Pattat N, et al. Annu Rev Microbiol, 1996. PMID 8905080

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. KduD encodes an oxidoreductase that converts both sugar and steroid substrates.
      Title: Escherichia coli kduD encodes an oxidoreductase that converts both sugar and steroid substrates.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables 11-deoxycorticosterone reductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables 2-deoxy-D-gluconate 3-dehydrogenase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables NAD binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within D-galacturonate catabolic process IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within D-glucuronate catabolic process IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    putative 2-keto-3-deoxy-D-gluconate dehydrogenase
    NP_417319.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      2982497..2983258 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_417319.1 putative 2-keto-3-deoxy-D-gluconate dehydrogenase [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_417319.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A5B9AQ27
      Conserved Domains (1) summary
      PRK08993
      Location:1 → 253
      PRK08993; 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase KduD
    Nucleotide Protein
    Heading Accession and Version

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