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    plsC 1-acylglycerol-3-phosphate O-acyltransferase PlsC [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 947496, updated on 3-Dec-2024

    Summary

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    Official Symbol
    plsC
    Official Full Name
    1-acylglycerol-3-phosphate O-acyltransferase PlsC
    Primary source
    ECOCYC:EG11377
    Locus tag
    b3018
    See related
    ASAP:ABE-0009910
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK3009; parF
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    Genomic context

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    Sequence:
    NC_000913.3 (3162744..3163481, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene radical SAM superfamily protein YgiQ Neighboring gene cell division protein FtsP Neighboring gene DNA topoisomerase IV subunit A Neighboring gene putative deoxycholate binding periplasmic protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Cell-Free Phospholipid Biosynthesis by Gene-Encoded Enzymes Reconstituted in Liposomes. Scott A, et al. PLoS One, 2016. PMID 27711229, Free PMC Article
    2. Alteration of the fatty acid substrate specificity of lysophosphatidate acyltransferase by site-directed mutagenesis. Morand LZ, et al. Biochem Biophys Res Commun, 1998 Mar 6. PMID 9514885
    3. Phospholipid synthesis in Escherichia coli. Characteristics of fatty acid transfer from acyl-acyl carrier protein to sn-glycerol 3-phosphate. Rock CO, et al. J Biol Chem, 1981 Jan 25. PMID 7005223
    4. Facilitated utilization of endogenously synthesized lysophosphatidic acid by 1-acylglycerophosphate acyltransferase from Escherichia coli. Kessels JM, et al. Biochim Biophys Acta, 1983 Sep 20. PMID 6351928
    5. Characterization of Escherichia coli cells deficient in 1-acyl-sn-glycerol-3- phosphate acyltransferase activity. Coleman J. J Biol Chem, 1990 Oct 5. PMID 2211622

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. N-terminus verified by Edman degradation on complete protein
      Title: Characterization of the Escherichia coli gene for 1-acyl-sn-glycerol-3-phosphate acyltransferase (plsC).
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables 1-acylglycerol-3-phosphate O-acyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables 1-acylglycerol-3-phosphate O-acyltransferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables 1-acylglycerol-3-phosphate O-acyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables acyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in CDP-diacylglycerol biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in phosphatidic acid biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within phosphatidic acid biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in phospholipid biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    1-acylglycerol-3-phosphate O-acyltransferase PlsC
    NP_417490.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      3162744..3163481 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_417490.1 1-acylglycerol-3-phosphate O-acyltransferase PlsC [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_417490.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      W1X3E3
      Conserved Domains (1) summary
      PRK15018
      Location:1 → 245
      PRK15018; 1-acyl-sn-glycerol-3-phosphate acyltransferase; Provisional
    Nucleotide Protein
    Heading Accession and Version

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