fadA 3-ketoacyl-CoA thiolase [Escherichia coli str. K-12 substr. MG1655] - Gene

Summary

Official Symbol: fadA
Official Full Name: 3-ketoacyl-CoA thiolase
Primary source: ECOCYC:EG10278
Locus tag: b3845
See related: ASAP:ABE-0012562
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage: Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as: ECK3837; oldA
Summary: FadR regulon. [More information is available at EcoGene: EG10278]. The beta subunit has one enzymatic activity associated with it and is part of a multienzyme complex. [More information is available at EcoCyc: EG10278].
NEW: Try the new Gene table
Try the new Transcript table

NC_000913.3 Genomic Context describing neighboring genes

Go to nucleotide: Graphics FASTA GenBank

Crystal structure of a thiolase from Escherichia coli at 1.8 A resolution has been reported.
Title: Crystal structure of a thiolase from Escherichia coli at 1.8 Å resolution.
N-terminus verified by Edman degradation on complete protein
Title: Nucleotide sequence of the fadA gene. Primary structure of 3-ketoacyl-coenzyme A thiolase from Escherichia coli and the structural organization of the fadAB operon.

Submit: New GeneRIF Correction

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables acetyl-CoA C-acyltransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables acetyl-CoA C-acyltransferase activity	IDA Inferred from Direct Assay more info	PubMed
enables acetyl-CoA C-acyltransferase activity	IEA Inferred from Electronic Annotation more info
enables acetyl-CoA C-acyltransferase activity	IMP Inferred from Mutant Phenotype more info	PubMed
enables acyltransferase activity	IEA Inferred from Electronic Annotation more info
enables acyltransferase activity, transferring groups other than amino-acyl groups	IEA Inferred from Electronic Annotation more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
involved_in fatty acid beta-oxidation	IBA Inferred from Biological aspect of Ancestor more info
involved_in fatty acid beta-oxidation	IDA Inferred from Direct Assay more info	PubMed
involved_in fatty acid beta-oxidation	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within fatty acid beta-oxidation	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within fatty acid catabolic process	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in fatty acid metabolic process	IEA Inferred from Electronic Annotation more info
involved_in lipid catabolic process	IEA Inferred from Electronic Annotation more info
involved_in phenylacetate catabolic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in small molecule metabolic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	IDA Inferred from Direct Assay more info	PubMed
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
part_of fatty acid beta-oxidation multienzyme complex	IDA Inferred from Direct Assay more info	PubMed
part_of fatty acid beta-oxidation multienzyme complex	IPI Inferred from Physical Interaction more info	PubMed

YP_026272.1

NEW Try the new Transcript table

The following sections contain reference sequences that belong to a specific genome build. Explain