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    tamA translocation and assembly module subunit TamA [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 948733, updated on 3-Dec-2024

    Summary

    Official Symbol
    tamA
    Official Full Name
    translocation and assembly module subunit TamA
    Primary source
    ECOCYC:G7874
    Locus tag
    b4220
    See related
    ASAP:ABE-0013809
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK4216; ytfM
    Summary
    Predicted 21 aa signal peptide is consistent with an observed secB-dependent precursor cleavage that is blocked by azide (Marani, 2006). [More information is available at EcoGene: EG12513]. YtfM, a homolog of YaeT and member of the Omp85 family , localizes to the outer membrane in Escherichia coli . [More information is available at EcoCyc: G7874].
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    Genomic context

    Sequence:
    NC_000913.3 (4442382..4444115)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene putative cadaverine/putrescine exporter Neighboring gene methionine sulfoxide reductase A Neighboring gene translocation and assembly module subunit TamB Neighboring gene gamma-glutamylamine cyclotransferase family protein YtfP Neighboring gene ChpS antitoxin of the ChpB-ChpS toxin-antitoxin system Neighboring gene endoribonuclease toxin ChpB

    Bibliography

    General gene information

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables protein binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in protein localization to outer membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in protein localization to outer membrane IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in protein secretion IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in protein secretion IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    part_of TAM protein secretion complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of TAM protein secretion complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of TAM protein secretion complex IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    is_active_in cell outer membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cell outer membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cell outer membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in outer membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    translocation and assembly module subunit TamA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      4442382..4444115
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_418641.1 translocation and assembly module subunit TamA [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_418641.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A8T6PQY4
      Conserved Domains (1) summary
      COG0729
      Location:1577
      TamA; Outer membrane translocation and assembly module TamA [Cell wall/membrane/envelope biogenesis]