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    paaD phenylacetate degradation protein [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 945959, updated on 3-Dec-2024

    Summary

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    Official Symbol
    paaD
    Official Full Name
    phenylacetate degradation protein
    Primary source
    ECOCYC:G6712
    Locus tag
    b1391
    See related
    ASAP:ABE-0004655
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK1388; ydbQ
    Summary
    PaaABCDE is a multi-subunit oxygenase that hydroxylates phenylacetyl-CoA. [More information is available at EcoGene: EG13738]. PaaA, PaaB, PaaC, and PaaD are predicted to be subunits of a phenylacetate-CoA oxygenase involved in phenylacetate catabolism . [More information is available at EcoCyc: G6712].
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    Genomic context

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    Sequence:
    NC_000913.3 (1455925..1456422)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene phenylacetyl-CoA 1,2-epoxidase subunit B Neighboring gene phenylacetyl-CoA 1,2-epoxidase, structural subunit Neighboring gene phenylacetyl-CoA 1,2-epoxidase, reductase subunit Neighboring gene putative 2,3-dehydroadipyl-CoA hydratase Neighboring gene putative ring 1,2-epoxyphenylacetyl-CoA isomerase (oxepin-CoA forming)

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genetic characterization of the phenylacetyl-coenzyme A oxygenase from the aerobic phenylacetic acid degradation pathway of Escherichia coli. Fernández C, et al. Appl Environ Microbiol, 2006 Nov. PMID 16997993, Free PMC Article
    2. Functional genomics by NMR spectroscopy. Phenylacetate catabolism in Escherichia coli. Ismail W, et al. Eur J Biochem, 2003 Jul. PMID 12846838
    3. Transcriptional regulation of the divergent paa catabolic operons for phenylacetic acid degradation in Escherichia coli. Ferrández A, et al. J Biol Chem, 2000 Apr 21. PMID 10766858
    4. The binary protein-protein interaction landscape of Escherichia coli. Rajagopala SV, et al. Nat Biotechnol, 2014 Mar. PMID 24561554, Free PMC Article
    5. Catabolism of phenylacetic acid in Escherichia coli. Characterization of a new aerobic hybrid pathway. Ferrández A, et al. J Biol Chem, 1998 Oct 2. PMID 9748275

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Process Evidence Code Pubs
    involved_in phenylacetate catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in phenylacetate catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    phenylacetate degradation protein

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      1455925..1456422
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_415909.4 phenylacetate degradation protein [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_415909.4

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A8T5ZYZ8
      Conserved Domains (1) summary
      TIGR02159
      Location:22 → 165
      PA_CoA_Oxy4; phenylacetate-CoA oxygenase, PaaJ subunit
    Nucleotide Protein
    Heading Accession and Version

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