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    speG spermidine N-acetyltransferase [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 946117, updated on 3-Dec-2024

    Summary

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    Official Symbol
    speG
    Official Full Name
    spermidine N-acetyltransferase
    Primary source
    ECOCYC:G6842
    Locus tag
    b1584
    See related
    ASAP:ABE-0005286
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK1579
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    Genomic context

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    Sequence:
    NC_000913.3 (1656184..1656744)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene putative transporter YnfA Neighboring gene DUF1283 domain-containing protein YnfB Neighboring gene PF06788 family lipoprotein YnfC Neighboring gene DUF1161 domain-containing protein YnfD

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Criticality of a conserved tyrosine residue in the SpeG protein from Escherichia coli. Le VTB, et al. Protein Sci, 2021 Jun. PMID 33826189, Free PMC Article
    2. Analysis of crystalline and solution states of ligand-free spermidine N-acetyltransferase (SpeG) from Escherichia coli. Filippova EV, et al. Acta Crystallogr D Struct Biol, 2019 Jun 1. PMID 31205017, Free PMC Article
    3. Expression, purification, crystallization and preliminary crystallographic analysis of spermidine acetyltransferase from Escherichia coli. Niiyama M, et al. Acta Crystallogr Sect F Struct Biol Cryst Commun, 2013 Aug. PMID 23908034, Free PMC Article
    4. Spermidine acetyltransferase is required to prevent spermidine toxicity at low temperatures in Escherichia coli. Limsuwun K, et al. J Bacteriol, 2000 Oct. PMID 10986239, Free PMC Article
    5. Properties and structure of spermidine acetyltransferase in Escherichia coli. Fukuchi J, et al. J Biol Chem, 1994 Sep 9. PMID 8077207

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Criticality of a conserved tyrosine residue in the SpeG protein from Escherichia coli.
      Title: Criticality of a conserved tyrosine residue in the SpeG protein from Escherichia coli.
    2. this paper describes structural analyses of SpeG isolated from Escherichia coli.
      Title: Analysis of crystalline and solution states of ligand-free spermidine N-acetyltransferase (SpeG) from Escherichia coli.
    3. N-terminus verified by Edman degradation on mature peptide
      Title: Properties and structure of spermidine acetyltransferase in Escherichia coli.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables acyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables acyltransferase activity, transferring groups other than amino-acyl groups IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables diamine N-acetyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables diamine N-acetyltransferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables diamine N-acetyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables identical protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables magnesium ion binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in coenzyme A metabolic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in polyamine catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in spermidine catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in spermine catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of diamine N-acetyltransferase complex IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    part_of protein-containing complex IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    spermidine N-acetyltransferase
    NP_416101.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      1656184..1656744
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_416101.1 spermidine N-acetyltransferase [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_416101.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A376U9N2
      Conserved Domains (1) summary
      PRK15130
      Location:1 → 186
      PRK15130; spermidine N1-acetyltransferase; Provisional
    Nucleotide Protein
    Heading Accession and Version

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