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    dcyD D-cysteine desulfhydrase [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 946831, updated on 17-Dec-2024

    Summary

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    Official Symbol
    dcyD
    Official Full Name
    D-cysteine desulfhydrase
    Primary source
    ECOCYC:G7038
    Locus tag
    b1919
    See related
    ASAP:ABE-0006389
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK1918; yedO
    Summary
    dcyD is a non-essential gene. [More information is available at EcoGene: EG14038]. D-cysteine desulfhydrase is involved in utilization of D-cysteine as a source of sulfur. [More information is available at EcoCyc: G7038].
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    Genomic context

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    Sequence:
    NC_000913.3 (1998494..1999480, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene cystine ABC transporter ATP binding subunit Neighboring gene cystine ABC transporter membrane subunit Neighboring gene cystine ABC transporter periplasmic binding protein Neighboring gene DNA-binding transcriptional regulator FliZ

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. D-Cysteine desulfhydrase of Escherichia coli. Purification and characterization. Nagasawa T, et al. Eur J Biochem, 1985 Dec 16. PMID 3908101
    2. Physiological comparison of D-cysteine desulfhydrase of Escherichia coli with 3-chloro-D-alanine dehydrochlorinase of Pseudomonas putida CR 1-1. Nagasawa T, et al. Arch Microbiol, 1988. PMID 3132906
    3. Role of D-cysteine desulfhydrase in the adaptation of Escherichia coli to D-cysteine. Soutourina J, et al. J Biol Chem, 2001 Nov 2. PMID 11527960
    4. Identification and functional analysis of Escherichia coli cysteine desulfhydrases. Awano N, et al. Appl Environ Microbiol, 2005 Jul. PMID 16000837, Free PMC Article
    5. A 460-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 40.1-50.0 min region on the linkage map. Itoh T, et al. DNA Res, 1996 Dec 31. PMID 9097040

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. N-terminus verified by Edman degradation on mature peptide
      Title: Role of D-cysteine desulfhydrase in the adaptation of Escherichia coli to D-cysteine.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables 3-chloro-D-alanine dehydrochlorinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables D-cysteine desulfhydrase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables D-cysteine desulfhydrase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables D-cysteine desulfhydrase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables carbon-sulfur lyase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables lyase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein homodimerization activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables pyridoxal phosphate binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within D-amino acid metabolic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in D-amino acid metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within D-cysteine catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within cellular response to sulfur starvation IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within sulfur compound metabolic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within sulfur utilization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    D-cysteine desulfhydrase
    NP_416429.4

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      1998494..1999480 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_416429.4 D-cysteine desulfhydrase [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_416429.4

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A376M6E2, A0A828PIB5, A0A8H9XLV7, A0A8S7CQF7, A0A8S7TR17
      Conserved Domains (1) summary
      PRK03910
      Location:4 → 328
      PRK03910; D-cysteine desulfhydrase; Validated
    Nucleotide Protein
    Heading Accession and Version

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