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    wcaC colanic acid biosynthesis galactosyltransferase WcaC [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 946579, updated on 17-Dec-2024

    Summary

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    Official Symbol
    wcaC
    Official Full Name
    colanic acid biosynthesis galactosyltransferase WcaC
    Primary source
    ECOCYC:G7102
    Locus tag
    b2057
    See related
    ASAP:ABE-0006811
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK2051
    Summary
    WcaC is believed to be a glycosyl transferase involved in colanic acid synthesis based on sequence similarity and its presence in a putative colanic acid synthesis operon . [More information is available at EcoCyc: G7102].
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    Genomic context

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    Sequence:
    NC_000913.3 (2130853..2132070, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene colanic acid biosynthesis acetyltransferase WcaF Neighboring gene GDP-Fuc:2/3-O-Ac-alpha-L-Fuc-(1->3)-alpha-D-Glc-PP-Und alpha-(1,4)-fucosyltransferase Neighboring gene colanic acid polymerase Neighboring gene colanic acid biosynthesis acetyltransferase WcaB Neighboring gene UDP-glucuronate:2-O-Ac-beta-D-Gal-(1->3)-alpha-L-Fuc-(1->4)-2/3-O-Ac-alpha-L-Fuc-(1->3)-beta-D-Glc-PP-Und beta-(1,3)-glucuronosyltransferase Neighboring gene protein-tyrosine kinase Wzc

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Biosynthesis and assembly of capsular polysaccharides in Escherichia coli. Whitfield C. Annu Rev Biochem, 2006. PMID 16756484
    2. Development of a biofilm production-deficient Escherichia coli strain as a host for biotechnological applications. Sung BH, et al. Appl Environ Microbiol, 2006 May. PMID 16672475, Free PMC Article
    3. Genome-wide analyses revealing a signaling network of the RcsC-YojN-RcsB phosphorelay system in Escherichia coli. Hagiwara D, et al. J Bacteriol, 2003 Oct. PMID 13129944, Free PMC Article
    4. Identification of the Functional Roles of Six Key Proteins in the Biosynthesis of Enterobacteriaceae Colanic Acid. Scott PM, et al. Biochemistry, 2019 Apr 2. PMID 30821147, Free PMC Article
    5. Organization of the Escherichia coli K-12 gene cluster responsible for production of the extracellular polysaccharide colanic acid. Stevenson G, et al. J Bacteriol, 1996 Aug. PMID 8759852, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables UDP-galactosyltransferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables hexosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within colanic acid biosynthetic process IGC
    Inferred from Genomic Context
    more info
    		 PubMed 
    involved_in lipopolysaccharide biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in slime layer polysaccharide biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    colanic acid biosynthesis galactosyltransferase WcaC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      2130853..2132070 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_416561.1 colanic acid biosynthesis galactosyltransferase WcaC [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_416561.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A8S7EG82
      Conserved Domains (1) summary
      TIGR04015
      Location:1 → 405
      WcaC; colanic acid biosynthesis glycosyl transferase WcaC
    Nucleotide Protein
    Heading Accession and Version

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