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    bcsC cellulose synthase outer membrane channel [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 948047, updated on 3-Dec-2024

    Summary

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    Official Symbol
    bcsC
    Official Full Name
    cellulose synthase outer membrane channel
    Primary source
    ECOCYC:EG12257
    Locus tag
    b3530
    See related
    ASAP:ABE-0011538
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK3515; yhjL
    Summary
    A 22 aa type I signal peptide is predicted. [More information is available at EcoGene: EG12257]. BcsC is involved in cellulose biosynthesis. [More information is available at EcoCyc: EG12257].
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    Genomic context

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    Sequence:
    NC_000913.3 (3685700..3689173, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene C4 dicarboxylate/orotate:H(+) symporter Neighboring gene c-di-GMP phosphodiesterase PdeK Neighboring gene endo-1,4-D-glucanase Neighboring gene cellulose synthase periplasmic subunit Neighboring gene cellulose synthase catalytic subunit Neighboring gene pseudo

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Architecture of the Cellulose Synthase Outer Membrane Channel and Its Association with the Periplasmic TPR Domain. Acheson JF, et al. Structure, 2019 Dec 3. PMID 31604608, Free PMC Article
    2. Tight modulation of Escherichia coli bacterial biofilm formation through controlled expression of adhesion factors. Da Re S, et al. Appl Environ Microbiol, 2007 May. PMID 17384304, Free PMC Article
    3. Systematic Localization of Escherichia coli Membrane Proteins. Sueki A, et al. mSystems, 2020 Mar 3. PMID 32127419, Free PMC Article
    4. The multicellular morphotypes of Salmonella typhimurium and Escherichia coli produce cellulose as the second component of the extracellular matrix. Zogaj X, et al. Mol Microbiol, 2001 Mar. PMID 11260463
    5. Analysis of the Escherichia coli genome. V. DNA sequence of the region from 76.0 to 81.5 minutes. Sofia HJ, et al. Nucleic Acids Res, 1994 Jul 11. PMID 8041620, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Process Evidence Code Pubs
    involved_in cellulose biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cell outer membrane HDA PubMed 
    located_in outer membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    cellulose synthase outer membrane channel

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      3685700..3689173 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. YP_026226.4 cellulose synthase outer membrane channel [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for YP_026226.4

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A377C6T1
      Conserved Domains (3) summary
      PRK11447
      Location:1 → 1157
      PRK11447; cellulose synthase subunit BcsC; Provisional
      sd00008
      Location:637 → 664
      TPR_YbbN; TPR repeat [structural motif]
      sd00006
      Location:303 → 331
      TPR; TPR repeat [structural motif]
    Nucleotide Protein
    Heading Accession and Version

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