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    dgoT D-galactonate:H(+) symporter [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 948196, updated on 17-Dec-2024

    Summary

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    Official Symbol
    dgoT
    Official Full Name
    D-galactonate:H(+) symporter
    Primary source
    ECOCYC:EG20053
    Locus tag
    b3691
    See related
    ASAP:ABE-0012072
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK3683; yidT
    Summary
    Major Facilitator Superfamily (MFS). [More information is available at EcoGene: EG11715]. DgoT is a probable galactonate transporter. [More information is available at EcoCyc: EG20053].
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    Genomic context

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    Sequence:
    NC_000913.3 (3870438..3871730, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene DUF1375 domain-containing putative lipoprotein YidQ Neighboring gene DUF3748 domain-containing galacturonate catabolism protein YidR Neighboring gene colicin M resistance protein Neighboring gene D-galactonate dehydratase Neighboring gene 2-dehydro-3-deoxy-6-phosphogalactonate aldolase Neighboring gene 2-dehydro-3-deoxygalactonokinase Neighboring gene DNA-binding transcriptional regulator DgoR

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Structures suggest a mechanism for energy coupling by a family of organic anion transporters. Leano JB, et al. PLoS Biol, 2019 May. PMID 31083648, Free PMC Article
    2. A functionally diverse enzyme superfamily that abstracts the alpha protons of carboxylic acids. Babbitt PC, et al. Science, 1995 Feb 24. PMID 7855594
    3. The utilisation of D-galactonate and D-2-oxo-3-deoxygalactonate by Escherichia coli K-12. Biochemical and genetical studies. Cooper RA. Arch Microbiol, 1978 Aug 1. PMID 211976
    4. D-Galactonate utilisation by enteric bacteria. The catabolic pathway in Escherichia coli. Deacon J, et al. FEBS Lett, 1977 May 15. PMID 324806
    5. Molecular and Functional Insights into the Regulation of d-Galactonate Metabolism by the Transcriptional Regulator DgoR in Escherichia coli. Singh B, et al. J Bacteriol, 2019 Feb 15. PMID 30455279, Free PMC Article

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables D-galactonate transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables solute:proton symporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables symporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within D-galactonate catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within D-galactonate transmembrane transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in proton transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    D-galactonate:H(+) symporter

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      3870438..3871730 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_418146.4 D-galactonate:H(+) symporter [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_418146.4

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A0J2DXH5, A0A0P7NFX3, A0A0V9LKS9, A0A140N4G8, A0A2H4TT17, A0A2K3TP68, A0A2W8GP70, A0A2X7F4J8, A0A377E1Q5, A0A4C4D468, A0A8B3M2L7, A0A8S7TFV9, A0AAD2S1D1, A0AAJ2Y6X3, A0AAP7P0F1
      Conserved Domains (1) summary
      TIGR00893
      Location:23 → 423
      2A0114; D-galactonate transporter
    Nucleotide Protein
    Heading Accession and Version

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