U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    hemG protoporphyrinogen oxidase [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 948331, updated on 3-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    hemG
    Official Full Name
    protoporphyrinogen oxidase
    Primary source
    ECOCYC:EG11485
    Locus tag
    b3850
    See related
    ASAP:ABE-0012577
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK3842; yihB
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    Sequence:
    NC_000913.3 (4034608..4035153)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene Xaa-Pro dipeptidase Neighboring gene IMPACT family member YigZ Neighboring gene K(+) transporter TrkH Neighboring gene 16S ribosomal RNA Neighboring gene tRNA-Ile

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Nucleotide sequence of the hemG gene involved in the protoporphyrinogen oxidase activity of Escherichia coli K12. Sasarman A, et al. Can J Microbiol, 1993 Dec. PMID 7916647
    2. Evidence for involvement of the electron transport system at a late step of anaerobic microbial heme synthesis. Jacobs NJ, et al. Biochim Biophys Acta, 1977 Jan 6. PMID 318855
    3. Quinones as hydrogen carriers for a late step in anaerobic heme biosynthesis in Escherichia coli. Jacobs NJ, et al. Biochim Biophys Acta, 1978 Dec 18. PMID 365243
    4. Mapping of a new hem gene in Escherichia coli K12. Săsărman A, et al. J Gen Microbiol, 1979 Aug. PMID 390093
    5. Nitrate, fumarate, and oxygen as electron acceptors for a late step in microbial heme synthesis. Jacobs NJ, et al. Biochim Biophys Acta, 1976 Oct 13. PMID 788792

    See all (21) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. N-terminus verified by Edman degradation on complete protein
      Title: Nucleotide sequence of the hemG gene involved in the protoporphyrinogen oxidase activity of Escherichia coli K12.
    Submit: New GeneRIF Correction

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables FMN binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables FMN binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables FMN binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables electron transfer activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables menaquinone-dependent protoporphyrinogen oxidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables menaquinone-dependent protoporphyrinogen oxidase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables menaquinone-dependent protoporphyrinogen oxidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxygen-dependent protoporphyrinogen oxidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within heme B biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in heme biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in heme biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within heme biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in porphyrin-containing compound biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within porphyrin-containing compound biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in protoporphyrinogen IX biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    colocalizes_with cytoplasmic side of plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    protoporphyrinogen oxidase
    NP_418292.1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      4034608..4035153
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_418292.1 protoporphyrinogen oxidase [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_418292.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A7L7EE66
      Conserved Domains (1) summary
      PRK11104
      Location:1 → 178
      hemG; menaquinone-dependent protoporphyrinogen IX dehydrogenase
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.