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    pdeC c-di-GMP phosphodiesterase PdeC [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 948568, updated on 3-Dec-2024

    Summary

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    Official Symbol
    pdeC
    Official Full Name
    c-di-GMP phosphodiesterase PdeC
    Primary source
    ECOCYC:EG11938
    Locus tag
    b4061
    See related
    ASAP:ABE-0013309
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK4053; yjcC
    Summary
    YjcC has a C-terminal putative cyclic-di-GMP phosphodiesterase EAL domain. [More information is available at EcoGene: EG11938]. YjcC is an inner membrane protein with two predicted transmembrane domains. [More information is available at EcoCyc: EG11938].
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    Genomic context

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    Sequence:
    NC_000913.3 (4275471..4277057)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene ssDNA-binding protein Neighboring gene uncharacterized protein YjcB Neighboring gene DNA-binding transcriptional dual regulator SoxS Neighboring gene DNA-binding transcriptional dual regulator SoxR Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Second messenger signalling governs Escherichia coli biofilm induction upon ribosomal stress. Boehm A, et al. Mol Microbiol, 2009 Jun. PMID 19460094
    2. Expression and Genetic Activation of Cyclic Di-GMP-Specific Phosphodiesterases in Escherichia coli. Reinders A, et al. J Bacteriol, 2016 Feb 1. PMID 26553851, Free PMC Article
    3. Transmembrane redox control and proteolysis of PdeC, a novel type of c-di-GMP phosphodiesterase. Herbst S, et al. EMBO J, 2018 Apr 13. PMID 29514851, Free PMC Article
    4. C-di-GMP: the dawning of a novel bacterial signalling system. Römling U, et al. Mol Microbiol, 2005 Aug. PMID 16045609
    5. Gene expression patterns and differential input into curli fimbriae regulation of all GGDEF/EAL domain proteins in Escherichia coli. Sommerfeldt N, et al. Microbiology (Reading), 2009 Apr. PMID 19332833

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables cyclic-guanylate-specific phosphodiesterase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables cyclic-guanylate-specific phosphodiesterase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables cyclic-guanylate-specific phosphodiesterase activity IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytosol RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 
    located_in outer membrane-bounded periplasmic space RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    c-di-GMP phosphodiesterase PdeC
    NP_418485.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      4275471..4277057
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_418485.1 c-di-GMP phosphodiesterase PdeC [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_418485.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A8S7SU89
      Conserved Domains (1) summary
      COG4943
      Location:1 → 526
      YjcC; Environmental sensor c-di-GMP phosphodiesterase, contains periplasmic CSS-motif sensor and cytoplasmic EAL domain [Signal transduction mechanisms]
    Nucleotide Protein
    Heading Accession and Version

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