murG N-acetylglucosaminyl transferase [Escherichia coli str. K-12 substr. MG1655] - Gene

Summary

Official Symbol: murG
Official Full Name: N-acetylglucosaminyl transferase
Primary source: ECOCYC:EG10623
Locus tag: b0090
See related: ASAP:ABE-0000322
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage: Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as: ECK0091
Summary: Essential gene, Mengin-Lecreulx(1991). [More information is available at EcoGene: EG10623]. The murG gene codes for the N-acetylglucosaminyl transferase responsible for the final intracellular step of peptidoglycan subunit assembly. [More information is available at EcoCyc: EG10623].
NEW: Try the new Gene table
Try the new Transcript table

NC_000913.3 Genomic Context describing neighboring genes

Go to nucleotide: Graphics FASTA GenBank

N-terminus verified by Edman degradation on mature peptide
Title: The murG gene of Escherichia coli codes for the UDP-N-acetylglucosamine: N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase involved in the membrane steps of peptidoglycan synthesis.
It is postulated that the involvement of MurG in the peptidoglycan synthesis concurs with two complexes, one implicated in cell elongation and the other in division.
Title: The essential peptidoglycan glycosyltransferase MurG forms a complex with proteins involved in lateral envelope growth as well as with proteins involved in cell division in Escherichia coli.

Submit: New GeneRIF Correction

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables UDP-N-acetyl-D-glucosamine:N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol 4-beta-N-acetylglucosaminlytransferase activity	IEA Inferred from Electronic Annotation more info
enables glycosyltransferase activity	IEA Inferred from Electronic Annotation more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity	IDA Inferred from Direct Assay more info	PubMed
enables undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity	IEA Inferred from Electronic Annotation more info
enables undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity	IMP Inferred from Mutant Phenotype more info	PubMed

Process	Evidence Code	Pubs
involved_in carbohydrate derivative biosynthetic process	IEA Inferred from Electronic Annotation more info
involved_in carbohydrate metabolic process	IEA Inferred from Electronic Annotation more info
involved_in cell division	IEA Inferred from Electronic Annotation more info
involved_in cell wall organization	IEA Inferred from Electronic Annotation more info
involved_in lipid glycosylation	IEA Inferred from Electronic Annotation more info
involved_in peptidoglycan biosynthetic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within peptidoglycan biosynthetic process	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in regulation of cell shape	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in plasma membrane	IEA Inferred from Electronic Annotation more info

NP_414632.1

NEW Try the new Transcript table

The following sections contain reference sequences that belong to a specific genome build. Explain