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    thiL thiamine monophosphate kinase [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 947387, updated on 17-Dec-2024

    Summary

    Official Symbol
    thiL
    Official Full Name
    thiamine monophosphate kinase
    Primary source
    ECOCYC:G6234
    Locus tag
    b0417
    See related
    ASAP:ABE-0001452
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK0411; thiJ
    Summary
    otherPDB (S. typhimurium): [More information is available at EcoGene: EG20227]. Thiamine phosphate kinase (ThiL) catalyzes the final step in thiamine biosynthesis. [More information is available at EcoCyc: G6234].
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    Genomic context

    Sequence:
    NC_000913.3 (435634..436611)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene 6,7-dimethyl-8-ribityllumazine synthase Neighboring gene transcription antitermination protein NusB Neighboring gene phosphatidylglycerophosphatase A Neighboring gene 1-deoxyxylulose-5-phosphate synthase YajO Neighboring gene 1-deoxy-D-xylulose-5-phosphate synthase

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables ATP binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables magnesium ion binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables magnesium ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables metal ion binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables thiamine-phosphate kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables thiamine-phosphate kinase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables thiamine-phosphate kinase activity IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    thiamine monophosphate kinase
    NP_414951.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      435634..436611
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_414951.1 thiamine monophosphate kinase [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_414951.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A8T6Q8Z7
      Conserved Domains (1) summary
      PRK05731
      Location:1322
      PRK05731; thiamine monophosphate kinase; Provisional