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    dtpD dipeptide:H(+) symporter DtpD [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 947368, updated on 17-Dec-2024

    Summary

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    Official Symbol
    dtpD
    Official Full Name
    dipeptide:H(+) symporter DtpD
    Primary source
    ECOCYC:G6378
    Locus tag
    b0709
    See related
    ASAP:ABE-0002420
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK0698; ybgH
    Summary
    Major Facilitator Superfamily (MFS). [More information is available at EcoGene: EG13304]. The YbgH protein is an uncharacterised member of the POT family of peptide transporters . [More information is available at EcoCyc: G6378].
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    Genomic context

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    Sequence:
    NC_000913.3 (741075..742556, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene H repeat-associated putative transposase YbfD Neighboring gene DUF1722 domain-containing protein YbgA Neighboring gene deoxyribodipyrimidine photolyase Neighboring gene radiation resistance protein YbgI Neighboring gene 5-oxoprolinase component B Neighboring gene 5-oxoprolinase component C

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Crystal structure of the E. coli peptide transporter YbgH. Zhao Y, et al. Structure, 2014 Aug 5. PMID 25066136
    2. DtpB (YhiP) and DtpA (TppB, YdgR) are prototypical proton-dependent peptide transporters of Escherichia coli. Harder D, et al. FEBS J, 2008 Jul. PMID 18485005
    3. Projection structure of DtpD (YbgH), a prokaryotic member of the peptide transporter family. Casagrande F, et al. J Mol Biol, 2009 Dec 11. PMID 19782088
    4. The POT family of transport proteins. Paulsen IT, et al. Trends Biochem Sci, 1994 Oct. PMID 7817396
    5. Microbial drug efflux proteins of the major facilitator superfamily. Saidijam M, et al. Curr Drug Targets, 2006 Jul. PMID 16842212

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables dipeptide transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables dipeptide transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables dipeptide transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables peptide transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables peptide:proton symporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables peptide:proton symporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables peptide:proton symporter activity RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 
    enables tripeptide transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in dipeptide transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within dipeptide transmembrane transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in dipeptide transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in peptide transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in protein transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in proton transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in tripeptide transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    dipeptide:H(+) symporter DtpD

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      741075..742556 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_415237.1 dipeptide:H(+) symporter DtpD [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_415237.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A376DEZ5
      Conserved Domains (1) summary
      PRK15462
      Location:1 → 493
      PRK15462; dipeptide permease
    Nucleotide Protein
    Heading Accession and Version

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