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    paaE phenylacetyl-CoA 1,2-epoxidase, reductase subunit [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 945962, updated on 17-Dec-2024

    Summary

    Official Symbol
    paaE
    Official Full Name
    phenylacetyl-CoA 1,2-epoxidase, reductase subunit
    Primary source
    ECOCYC:G6713
    Locus tag
    b1392
    See related
    ASAP:ABE-0004657
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK1389; ydbR
    Summary
    PaaABCDE is a multi-subunit oxygenase that hydroxylates phenylacetyl-CoA. [More information is available at EcoGene: EG13739]. PaaE may be an NAD(P)H-dependent electron donor to the terminal oxygenase composed of PaaA, PaaB, and PaaC, plus a PaaD subunit , which is involved in phenylacetate catabolism . [More information is available at EcoCyc: G6713].
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    Genomic context

    Sequence:
    NC_000913.3 (1456430..1457500)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene phenylacetyl-CoA 1,2-epoxidase, structural subunit Neighboring gene phenylacetate degradation protein Neighboring gene putative 2,3-dehydroadipyl-CoA hydratase Neighboring gene putative ring 1,2-epoxyphenylacetyl-CoA isomerase (oxepin-CoA forming) Neighboring gene 3-hydroxyadipyl-CoA dehydrogenase Neighboring gene phenylacetyl-CoA thioesterase

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables 2 iron, 2 sulfur cluster binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables 2 iron, 2 sulfur cluster binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables 2 iron, 2 sulfur cluster binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables flavin adenine dinucleotide binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables flavin adenine dinucleotide binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables oxidoreductase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in phenylacetate catabolic process IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in phenylacetate catabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in phenylacetate catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cytosol NAS
    Non-traceable Author Statement
    more info
    PubMed 
    part_of phenylacetyl-CoA 1,2-epoxidase complex IPI
    Inferred from Physical Interaction
    more info
    PubMed 

    General protein information

    Preferred Names
    phenylacetyl-CoA 1,2-epoxidase, reductase subunit
    NP_415910.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      1456430..1457500
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_415910.1 phenylacetyl-CoA 1,2-epoxidase, reductase subunit [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_415910.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A377E5K7
      Conserved Domains (1) summary
      TIGR02160
      Location:4351
      PA_CoA_Oxy5; phenylacetate-CoA oxygenase/reductase, PaaK subunit